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| Product | Description | |
|---|---|---|
| Pyroxamide | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Pyroxamide | Pyroamide is a histone decetylase inhibitor (HDCi), a novel class of anti-neoplastic agent that acts by enhancing acetylation of histones, promoting uncoiling of chromatin and activation of genes implicated in the regulation of cell survival such as poliferation, differentiation and apoptosis. Pyroamide is known to potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells. Group: Biochemicals. Alternative Names: N1-hydroxy-N8-3-pyridinyloctane diamide; N-hydroxy-N-3-pyridinyloctane diamide. Grades: Highly Purified. CAS No. 382180-17-8. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Pyroxamide | Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. Synonyms: N1-hydroxy-N8-(pyridin-3-yl)octanediamide; N-Hydroxy-N'-3-pyridinyloctanediamide; Octanedioic acid hydroxyamide pyridin-3-ylamide. Grades: 99%. CAS No. 382180-17-8. Molecular formula: C13H19N3O3. Mole weight: 265.313. |  |
| Pyroxamide (N1-hydroxy-N8-3-pyridinyl-octanediamide) | Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC50=100nm). It induces growth suppression and cell death of certain types of cancer cells in culture. Group: Biochemicals. Grades: Highly Purified. CAS No. 382180-17-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
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