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| Product | Description | |
|---|---|---|
| QS11 | QS11 contains a planar purine ring with C2, C6, and N9-positions substituted. QS11, a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor, ) was demonstrated to synergize with Wnt proteins to activate b-catenin signaling. Synonyms: (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol; QS 11; QS-11; QS 11 (QS11,BML-WN117); (2S)-2-{[9-(4-Biphenylylmethyl)-2-(2,3-dihydro-1H-inden-5-yloxy)-9H-purin-6-yl]amino}-3-phenyl-1-propanol; J-501013. Grades: >98%. CAS No. 944328-88-5. Molecular formula: C36H33N5O2. Mole weight: 567.68. |  |
| QS11 (QS 11, QS-11, (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9Hpurin-6-ylamino]-3-phenyl-propan-1-ol) | Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/b-catenin signaling pathway. The Wnt/b-catenin signaling pathway regulates cell fate and behavior during embryogenesis, adult tissue homeostasis, and regeneration. Group: Biochemicals. Alternative Names: (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9Hpurin-6-ylamino]-3-phenyl-propan-1-ol. Grades: Highly Purified. CAS No. 944328-88-5. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| QS-1189 | QS-1189 is a reversible, high selective, orally available cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. QS-1189 exhibits antitumor activity via modulation of transcription and cell cycle. Uses: Antitumor agent. Synonyms: QS-1189; QS 1189; QS1189. | |
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