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| Product | Description | |
|---|---|---|
| Quinacrine | Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase ( IC 50 : 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm) [1] [2] [3] [4] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acriquine. CAS No. 83-89-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13735. |  |
| Quinacrine | Quinacrine is a PLA2 (phophoslipase A2) inhibitor that inhibits NF-κB and activates p53 signaling, thereby inducing apoptosis. Synonyms: 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-; Acridine, 6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy-; N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine; (±)-Quinacrine; 6-Chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxyacridine; Acrichin; Acrinamine; Acriquine; Akrichin; Antimalarina; Atabrine; Haffkinine; Italchine; Mepacrine; N4-(6-Chloro-2-methoxyacridin-9-yl)-N1,N1-diethylpentane-1,4-diamine; ST 439. Grades: ≥95%. CAS No. 83-89-6. Molecular formula: C23H30ClN3O. Mole weight: 399.96. |  |
| Quinacrine-d10 | 2H Labeled Compounds. Alternative Names: N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-d10-1,4-pentanediamine;6-Chloro-9-[[4-(diethyl-d10-amino)-1-methylbutyl]amino]-2-methoxyacridine;Mepacrine-d10. CAS No. 1189976-99-5. Molecular formula: C23H20D10ClN3O. Mole weight: 410.02. Catalog: ACM1189976995. |  |
| Quinacrine dihydrochloride | Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepacrine dihydrochloride; SN-390 dihydrochloride. CAS No. 69-05-6. Pack Sizes: 100 mg. Product ID: HY-13735A. | |
| Quinacrine Dihydrochloride | Quinacrine 2HCl is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. It is a non-selective MAO-A/B inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 69-05-6. Pack Sizes: 50mg, 500mg. Molecular Formula: C23H30ClN3O 2(HCl). US Biological Life Sciences. |  Worldwide |
| Quinacrine Dihydrochloride Dihydrate | Quinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 6151-30-0. Pack Sizes: 10g, 25g. Molecular Formula: C23H36Cl3N3O3, Molecular Weight: 508.91. US Biological Life Sciences. | Worldwide |
| Quinacrine hydrochloride | Quinacrine dihydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53. Synonyms: atabrine dihydrochloride; mepacrine dihydrochoride; SN 390. CAS No. 69-05-6. Molecular formula: C23H30ClN3O.2HCl. Mole weight: 472.88. | |
| Quinacrine hydrochloride hydrate | Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate. CAS No. 6151-30-0. Pack Sizes: 100 mg. Product ID: HY-13735B. | |
| Quinacrine mustard dihydrochloride | Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 4213-45-0. Pack Sizes: 5 mg. Product ID: HY-W127705. | |
| Monodesethyl Quinacrine, Dihydrochloride | A metabolite of Quinacrine, an antimalarial compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| rac Quinacrine-d10 Dihydrochloride | Anthelmintic; antimalarial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H20D10ClN3O 2(HCl). US Biological Life Sciences. | Worldwide |
| rac Quinacrine-d10 (N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-d10-1,4-pentanediamine, 6-Chloro-9-[[4-(diethyl-d10-amino)-1-methylbutyl]amino]-2-methoxyacridine, Mepacrine-d10) | Anthelmintic; antimalarial. Group: Biochemicals. Alternative Names: N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-d10-1,4-pentanediamine; 6-Chloro-9-[[4-(diethyl-d10-amino)-1-methylbutyl]amino]-2-methoxyacridine; Mepacrine-d10. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-(2-Chloroethylazaniumyl)ethyl-(6-chloro-2-methoxyacridin-9-yl)azaniumdichloride | Heterocyclic Organic Compound. Alternative Names: Quinacrine ethyl M/2, ICR 171, ICR-125, CID24896, LS-14299, 9-(2-((2-Chloroethyl)amino)ethylamino)-6-chloro-2-methoxyacridine, dihydrochloride, Acridine, 9-(2-((2-chloroethyl)amino)ethylamino)-6-chloro-2-methoxy-, dihydrochloride, 10072-24-9. CAS No. 10072-24-9. Molecular formula: C18H21Cl4N3O. Mole weight: 437.191 g/mol. Purity: 0.96. IUPACName: 2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium dichloride. Canonical SMILES: COC1=CC2=C (C3=C (C=C (C=C3) Cl) N=C2C=C1) [NH2+]CC[NH2+]CCCl. [Cl-]. [Cl-]. Catalog: ACM10072249. | |
| Floxacrine | Floxacrine is drug candidate for chemoprophylaxis of malaria. It is also a particular anthelminthic drug derived from quinacrine. Uses: Floxacrine is drug candidate for chemoprophylaxis of malaria. it is also a particular anthelminthic drug derived from quinacrine. Synonyms: HOE-991; Floxacrina; Floxacrinum; 7-Chloro-3,4-dihydro-10-hydroxy-3-[p-(trifluoromethyl)phenyl]-1,9(2H,10H)-acridinedione. Grades: 98%. CAS No. 53966-34-0. Molecular formula: C20H13ClF3NO3. Mole weight: 407.77. | |
| Hydroxychloroquine | An antimalarial; antirheumatic; lupus erythematosus suppressant. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.2 Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus.12 Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. It was developed during World War II as a derivative of quinacrine with less severe side effects. Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. Hydroxychloroquine was granted FDA approval on 18 April 1955. Hydroxychloroquine is indicated for the prophylaxis of malaria where chloroquine resistance is not reported, treatment of uncomplicated malaria (caused by P. falciparum, P. malariae, P. ovale, or P. vivax), chronic discoid lupus erythematosus, systemÂ… Group: Biochemicals. Alternative Names: 2-[{4-[ (7-Chloroquinolin-4-yl)amino]pentyl} (ethyl)amino]ethanol; 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline; Plaquenil; Oxichloroquine; Oxychloro. Grades: Highly Purified. CAS No. 118-42-3. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C??H??ClN?O, Molecular Weight: 335.87. US Biological Life Sciences. | Worldwide |
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