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QuinidineSulfate, is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial. Group: Biochemicals. Grades: Highly Purified. CAS No. 747-45-5. Pack Sizes: 1g, 10g. Molecular Formula: C20H24N2O2.H2SO4. US Biological Life Sciences.
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Quinidinesulfate dihydrate
25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C40H48N4O4 ·H2O4S ·2H2O. CAS No. 6591-63-5. Prepack ID 18984634-25g. Molecular Weight 782.94. See USA prepack pricing.
Quinidinesulfate dihydrate
Quinidine is a voltage-gated sodium channel blocker, exhibiting antimuscarinic and antimalarial properties. Synonyms: Chinidin Sodium; Pitayine Sodium; β-quinine Sodium; (+)-quinidine Sodium; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol sulfuric acid dihydrate. CAS No. 6591-63-5. Molecular formula: C40H48N4O4·H2SO4·2H2O. Mole weight: 782.94.
Quinidinesulfate dihydrate
Quinidinesulfate dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 6591-63-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C40H48N4O4·H2O4S·2H2O. US Biological Life Sciences.
Worldwide
QuinidineSulfate Dihydrate
antiarrhythmic, antimalarialQuinidinesulfate is the prototype of antiarrhythmicdrugs and a class IA antiarrhythmic agent according to theVaughan Williams classification. It reduces Na+ current bybinding the open ion channels (i.e., state A). The decreasedNa+entry into the myocardial cell depresses phase 4 diastolicdepolarization and shifts the intracellular threshold potentialtoward zero. These combined actions diminish thespontaneous frequency of pacemaker tissues, depress theautomaticity of ectopic foci, and, to a lesser extent, reduceimpulse formation in the SA node. This last action results inbradycardia. During the spike action potential, quinidinesulfate decreases transmembrane permeability to passiveinflux of Na+, thus slowing the process of phase 0 depolarization,which decreases conduction velocity. This is shownas a prolongation of the QRS complex of electrocardiograms.Quinidinesulfate also prolongs action potential duration,which results in a proportionate increase in the QTinterval. It is used to treat supraventricular and ventricularectopic arrhythmias, such as atrial and ventricular prematurebeats, atrial and ventricular tachycardia, atrial flutter, andatrial fibrillation. Group: Quinoline alkaloids. Alternative Names: 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol hemisulfate hydrate. CAS No. 6591-63-5. Molecular formula: C40H54N4O10S. Mole weight: 782.9. Purity: 98%+. IUPACName:
Quinidine
Quinidine occurs in cinchona bark to about0.25-0.3% and also in cuprea bark. It is present in quinine sulfate mother liquor. Itis formed by isomerization of quinine. Itis used in the prevention of certain cardiacarrhythmias.Primary indications for the use of quinidine include (1) abolition of premature complexes that have an atrial, A-V junctional, or ventricular origin; (2) restoration of normal sinus rhythm in atrial flutter and atrial fibrillation after controlling the ventricular rate with digitalis; (3) maintenance of normal sinus rhythm after electrical conversion of atrial arrhythmias; (4) prophylaxis against arrhythmias associated with electrical countershock; (5) termination of ventricular tachycardia; and (6) suppression of repetitive tachycardia associated with Wolff- Parkinson-White (WPW) syndrome. Although quinidine often is successful in producing normal sinus rhythm, its administration in the presence of a rapid atrial rate (flutter and possibly atrial fibrillation) can lead to a further and dangerous increase in the ventricular rate secondary to inhibition of basal vagal tone upon the A-V node. For this reason, digitalis should be used before quinidine when one is attempting to convert atrial flutter or atrial fibrillation to normal sinus rhythm. Group: Heterocyclic organic compound. Alternative Names: (8R,9S)-6'-Methoxycinchonan-9-ol. CAS No. 56-54-2. Molecular formula: C20H24N2O2. Mole weight: 324.4. Appearanc
Quinine sulfate
Quinidinesulfate is an antiarrhythmic agent. Quinidinesulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidinesulfate is also a K + channel blocker with an IC 50 of 19.9 μM. Quinidinesulfate can be used for malaria research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 549-56-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B1751B.
Quinine Sulfate Dihydrate
Primary alkaloid of various species of Cinchona (Rubiaceae). Optical isomer of Quinidine. Antimalarial; muscle relaxant (skeletal). Group: Biochemicals. Grades: Highly Purified. CAS No. 6119-70-6. Pack Sizes: 1g. US Biological Life Sciences.
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