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Quinidine sulfate Quick inquiry Where to buy Suppliers range | United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & Metrological Institutes Standards; British Pharmacopoeia; European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: Cinchonan-9-ol, 6'-methoxy-, (9S)-, sulfate (2:1) (salt), dihydrate (9CI), bis[(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol] sulfate dihydrate, Quinidine, sulfate, hydrate (2:1:2) (8CI),Quinidine sulfate dihydrate, Cinchonan-9-ol, 6'-methoxy-, (9S)-, sulfate, hydrate (2:1:2). CAS No. 6591-63-5. Pack Sizes: 500MG. IUPAC Name: (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;dihydrate. Molecular formula: 2C20H24N2O2.2H2O.H2O4S. Mole weight: 782.94. Catalog: APS6591635. SMILES: O. O. COc1ccc2nccc ([C@H] (O) [C@H]3C[C@@H]4CCN3C[C@@H]4C=C) c2c1. COc5ccc6nccc ([C@H] (O) [C@H]7C[C@@H]8CCN7C[C@@H]8C=C) c6c5. OS (=O) (=O) O. Format: Neat. | |
Quinidine Sulfate Quick inquiry Where to buy Suppliers range | Quinidine Sulfate, is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial. Group: Biochemicals. Grades: Highly Purified. CAS No. 747-45-5. Pack Sizes: 1g, 10g. Molecular Formula: C20H24N2O2.H2SO4. US Biological Life Sciences. | Worldwide |
QUINIDINE SULFATE Quick inquiry Where to buy Suppliers range | Quinidine Sulfate. Categories: Quinidine Sulfate. | |
Quinidine sulfate dihydrate Quick inquiry Where to buy Suppliers range | 25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C40H48N4O4 ·H2O4S ·2H2O. CAS No. 6591-63-5. Prepack ID 18984634-25g. Molecular Weight 782.94. See USA prepack pricing. | |
Quinidine sulfate dihydrate Quick inquiry Where to buy Suppliers range | Quinidine is a voltage-gated sodium channel blocker, exhibiting antimuscarinic and antimalarial properties. Synonyms: Chinidin Sodium; Pitayine Sodium; β-quinine Sodium; (+)-quinidine Sodium; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol sulfuric acid dihydrate. CAS No. 6591-63-5. Molecular formula: C40H48N4O4·H2SO4·2H2O. Mole weight: 782.94. | |
Quinidine sulfate dihydrate Quick inquiry Where to buy Suppliers range | Quinidine sulfate dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 6591-63-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C40H48N4O4·H2O4S·2H2O. US Biological Life Sciences. | Worldwide |
Quinidine Sulfate Dihydrate Quick inquiry Where to buy Suppliers range | Quinidine Sulfate Dihydrate. Uses: antiarrhythmic, antimalarialQuinidine sulfate is the prototype of antiarrhythmicdrugs and a class IA antiarrhythmic agent according to theVaughan Williams classification. It reduces Na+ current bybinding the open ion channels (i.e., state A). The decreasedNa+entry into the myocardial cell depresses phase 4 diastolicdepolarization and shifts the intracellular threshold potentialtoward zero. These combined actions diminish thespontaneous frequency of pacemaker tissues, depress theautomaticity of ectopic foci, and, to a lesser extent, reduceimpulse formation in the SA node. This last action results inbradycardia. During the spike action potential, quinidinesulfate decreases transmembrane permeability to passiveinflux of Na+, thus slowing the process of phase 0 depolarization,which decreases conduction velocity. This is shownas a prolongation of the QRS complex of electrocardiograms.Quinidine sulfate also prolongs action potential duration,which results in a proportionate increase in the QTinterval. It is used to treat supraventricular and ventricularectopic arrhythmias, such as atrial and ventricular prematurebeats, atrial and ventricular tachycardia, atrial flutter, andatrial fibrillation. Alternative Names: 2C20H24N2O2.2H2O.H2SO4; Cinchonan-9-ol, 6'-methoxy-, (9S)-, sulfate (2:1) (salt), dihydrate; AC1Q59CF; J13S2394HE; Quinidine sulfate hydrate; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; CHEMBL3707183; Quinidine sulfate monohydrate; Cinchonan-9-ol, 6'-methoxy-, (9S)-, sulfate (2:1) (salt), monohydrate; Quinidine sulfate (2:1) (salt) dihydrate. CAS No. 6591-63-5. Molecular formula: C40H54N4O10S. Mole weight: 782.95g/mol. IUPAC Name: (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;dihydrate. Rotatable Bond Count: 8. Exact Mass: 782.356g/mol. Solubility: Slightly sol in water and soluble in alcohol. SMILES: COC1=CC2=C (C=CN=C2C=C1)C (C3CC4CCN3CC4C=C)O. COC1=CC2=C (C=CN=C2C=C1)C (C3CC4CCN3CC4C=C)O. O. O. OS (=O) (=O)O. InChI: InChI=1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19+,20- | |
Quinidine Quick inquiry Where to buy Suppliers range | Quinidine. Uses: Quinidine occurs in cinchona bark to about0.25-0.3% and also in cuprea bark. It is present in quinine sulfate mother liquor. Itis formed by isomerization of quinine. Itis used in the prevention of certain cardiacarrhythmias.Primary indications for the use of quinidine include (1) abolition of premature complexes that have an atrial, A-V junctional, or ventricular origin; (2) restoration of normal sinus rhythm in atrial flutter and atrial fibrillation after controlling the ventricular rate with digitalis; (3) maintenance of normal sinus rhythm after electrical conversion of atrial arrhythmias; (4) prophylaxis against arrhythmias associated with electrical countershock; (5) termination of ventricular tachycardia; and (6) suppression of repetitive tachycardia associated with Wolff- Parkinson-White (WPW) syndrome. Although quinidine often is successful in producing normal sinus rhythm, its administration in the presence of a rapid atrial rate (flutter and possibly atrial fibrillation) can lead to a further and dangerous increase in the ventricular rate secondary to inhibition of basal vagal tone upon the A-V node. For this reason, digitalis should be used before quinidine when one is attempting to convert atrial flutter or atrial fibrillation to normal sinus rhythm. Group: Heterocyclic Organic Compound. Alternative Names: SCHEMBL15943; Auriquin; FT-0082277; AC1L9AHW; NCGC00091231-01; 6470-EP2277872A1; PubChem7994; AKOS015920101; SC-88763; quinidina. CAS No. 56-54-2. Molecular formula: C20H24N2O2. Mole weight: 324.424g/mol. IUPAC Name: (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. Rotatable Bond Count: 4. Exact Mass: 324.184g/mol. EC Number: 200-279-0. Melting Point: 331 to 336 ° F (NTP, 1992);174-175 deg C after drying of solvated crystals;174°C. Solubility: less than 0.1 mg/mL at 64° F (NTP, 1992);8.15e-04 M;1 g /quinidine/ dissolves in about 36 ml alcohol, 56 ml ether, 1.6 ml chloroform; very soluble in methanol; practically insoluble in petroleum ether.;Soluble in benzene;In water, 140 mg/l @ 25 deg C;3.34e-01 g/L;>48.7 [ug/mL]. SMILES: COC1=CC2=C (C=CN=C2C=C1)C (C3CC4CCN3CC4C=C)O. InChI: InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,1 | |
Quinidine Quick inquiry Where to buy Suppliers range | Fluorescence/Luminescence Spectroscopy; API Standards; Impurity Standards; Pharmaceutical Toxicology. Uses: For analytical and research use. Group: reagents. Alternative Names: Conchinine, Quinidine Imp. A (EP), beta-Quinine, (8R,9S)-Quinidine, (+)-Quinidine, Conchinin, Quinine Imp. A (EP), Cinquin, Quinine Dihydrochloride Imp. A (EP), Pitayin, Pitayine,Quinidine Sulfate Imp. A (EP), Quindine, beta-Quinidine, Chinidin, Kinidin, Quinidine, Conquinine. Grades: anhydrous. CAS No. 56-54-2. Pack Sizes: 5G, 25G. IUPAC Name: (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. | |
Quinine Quick inquiry Where to buy Suppliers range | Quinine. Uses: Quinine occurs in the dried stems or rootbarks of cinchona (Cinchona ledgerianaMoens). It is used in the treatment of malaria.It is also used as an analgesic and antipyreticagent.A quinolinemethanol from the bark of the Cinchona tree; the laevorotatory stereoisomer of quinidine. Formulated as the sulfate, bisulfate or ethylcarbonate for oral use and as the dihydrochloride for parenteral administration. The salts are highly soluble in water.Falciparum malaria (alone or in combination with tetracycline, doxycycline, clindamycin or pyrimethamine-sulfadoxine) Babesiosis (in combination with clindamycin) It is particularly used in cerebral malaria if chloroquine resistance is suspected (Ch. 62). It is not recommended for treatment of uncomplicated falciparum malaria. Alternative Names: ZINC3831404; Coco-Quinine; UNII-A7V27PHC7A; Quinine sulphate; 6-Methoxycinchonine; Quinine tannate; SC-00760; Quinine, 90%; ACN-048717; (R)-(6-methoxy-4-quinolyl)-[(2S,4S,5R)-5-vinylquinuclidin-2-yl]methanol. CAS No. 130-95-0. Molecular formula: C20H24O2N2;C20H24N2O2. Mole weight: 324.424g/mol. IUPAC Name: (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. Rotatable Bond Count: 4. Exact Mass: 324.184g/mol. EC Number: 205-003-2. Melting Point: 177 deg C (some decomposition);57°C. Solubility: In water, 500 mg/L at 15 deg C;1 g dissolves in: 1900 mL water, 760 mL boiling water;1 g dissolves in: 80 mL benzene (18 mL at 50 deg C), 1.2 mL chloroform, 250 mL dry ether, 20 mL glycerol, 0.8 mL alcohol, 1900 mL of 10% ammonia water; almost insoluble in petroleum ether;Soluble in ether, chloroform, carbon disulfide, glycerol, alkalies, and acids (with formation of salts);Sol in pyrimidine;3.34e-01 g/L. SMILES: COC1=CC2=C (C=CN=C2C=C1)C (C3CC4CCN3CC4C=C)O. InChI: InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1. InChIKey: LOUPRKONTZGTKE-WZBLMQSHSA-N. H-Bond Donor: 1. H-Bond Acceptor: 4. Monoisotopic Mass: 324.184g/mol. | |
Quinine Sulfate Dihydrate Quick inquiry Where to buy Suppliers range | Primary alkaloid of various species of Cinchona (Rubiaceae). Optical isomer of Quinidine. Antimalarial; muscle relaxant (skeletal). Group: Biochemicals. Grades: Highly Purified. CAS No. 6119-70-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |