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| Product | Description | |
|---|---|---|
| Raclopride | Raclopride, also known as FLA 870, is a selective and potent dopamine D2/D3 receptor antagonist. It has high affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Uses: Antipsychotic agents. Synonyms: 3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide; (-)-Raclopride; FLA 870; FLA870; FLA-870; Benzamide, 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxy-; Benzamide, 3,5-dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxy-, (S)-; (S)-3,5-Dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide. Grades: ≥99% by HPLC. CAS No. 84225-95-6. Molecular formula: C15H20Cl2N2O3. Mole weight: 347.24. |  |
| Raclopride | Raclopride. Group: Biochemicals. Grades: Purified. CAS No. 84225-95-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Raclopride | Raclopride is a dopamine D 2 / D 3 receptor antagonist with potential antipsychotic effects. Raclopride binds to D 2 and D 3 receptor s with K i s of 1.8 nM and 3.5 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84225-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103414. |  |
| (S)-(-)-Raclopride (Dopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride) | D2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32nM. Group: Biochemicals. Grades: Highly Purified. CAS No. 84225-95-6. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| Amisulpride hydrochloride | Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. It has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM. It is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. It has been approved in February 2002 by FDA. Uses: Amisulpride hydrochloride is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. Synonyms: DAN 2163 hydrochloride; DAN2163 hydrochloride; DAN-2163 hydrochloride; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride. Grades: >98%. CAS No. 81342-13-4. Molecular formula: C17H28N3O4SCl. Mole weight: 405.94. | |
| Rac1 Inhibitor W56 | Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Synonyms: FLA 870; FLA-870; FLA870; Raclopride tartrate; MVDGKPVNLGLWDTAG. Grades: >97%. CAS No. 1095179-01-3. Molecular formula: C74H117N19O23S. Mole weight: 1671.93. | |
| S-14506 hydrochloride | S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT 2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286369-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110024. | |
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