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Ralinepag Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC 50 s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD811. CAS No. 1187856-49-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16751. MedChemExpress MCE
Ralinepag This active molecular is a Epoprostenol receptor agonist which is an investigational drug candidate developed by Arena and intended for the treatment of vasospastic diseases, for an example, Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin which elicits a potent vasodilation and inhibits platelet aggregation when binding to this receptor. In Jan 2015, Phase-II clinical trials in Pulmonary arterial hypertension in USA was on going. In Jul 2015, Phase-II clinical trials in Pulmonary arterial hypertension in Spain was on going. In Jul 2015, Arena initiated enrolment in a phase II extension trial for Pulmonary arterial hypertension in USA, Czech Republic, Hungary, Poland. Uses: Pulmonary arterial hypertension. Synonyms: 2- [ [4- [ [ (4-chlorophenyl) -phenylcarbamoyl] oxymethyl] cyclohexyl] methoxy] acetic acid,APD-811; APD 811; APD811; Ralinepag. Grades: 98%. CAS No. 1187856-49-0. Molecular formula: C23H26ClNO5. Mole weight: 431.91. BOC Sciences 9

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