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Ranimustine is a chloroethylnitrosourea derivative that inhibits proliferation and growth of tumor cells by alkylation and cross-linkage of DNA strands of tumor cells. Synonyms: Ranomustine. Cymer; Cymerin. MCNU. Grades: >98%. CAS No. 58994-96-0. Molecular formula: C10H18ClN3O7. Mole weight: 327.72.
cis-4-Hydroxy-lomustine
cis-4-Hydroxy-lomustine is an impurity of lomustine which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine. Synonyms: 1-(2-Chloroethyl)-3-(cis-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(cis-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239724; cis-4-Hydroxy CCNU. Grades: > 95%. CAS No. 52049-26-0. Molecular formula: C9H16ClN3O3. Mole weight: 249.69.
Lomustine
Chloroethylnitrosourea derivative with antitumor activity. Similar to carmustine, chlorozotocin, nimustine, ranimustine. Antineoplastic. Group: Biochemicals. Alternative Names: N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea. Grades: Highly Purified. CAS No. 13010-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
As an intermediate in the synthesis of Ranimustine, Methyl 6-[[[(2-Chloroethyl)amino]carbonyl]amino]-6-deoxy-α-D-glucopyranoside is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera. It can be used in biological study of synthesis of anti-EGFR antibody-drug conjugates. And it can also be used in therapeutic use and biological study of BCMA (B-Cell Maturation Antigen) antigen binding proteins. Synonyms: 1-(2-Chloroethyl)-3-(((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl)urea. CAS No. 58994-95-9. Molecular formula: C10H19ClN2O6. Mole weight: 298.72.
Methyl 6-Azido-6-deoxy-α-D-glucopyranoside
As an intermediate in the synthesis of Ranimustine, Methyl 6-Azido-6-deoxy-α-D-glucopyranoside is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera. It can be used in biological study of synthesis of anti-EGFR antibody-drug conjugates. It can also be used in therapeutic use and biological study of BCMA (B-Cell Maturation Antigen) antigen binding proteins. Synonyms: α-D-Methyl 6-Azido-6-deoxy-glucopyranoside. CAS No. 23701-87-3. Molecular formula: C7H14N3O5. Mole weight: 220.2.
As an intermediate in the synthesis of Ranimustine, Methyl α-D-Glucopyranoside 6-(4-Methylbenzenesulfona?te) is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera. It can be used in biological study of synthesis of anti-EGFR antibody-drug conjugates. It can also be used in therapeutic use and biological study of BCMA (B-Cell Maturation Antigen) antigen binding proteins. Synonyms: α-D-Methyl Glucopyranoside 6-p-Toluenesulfonate; ((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl)methyl 4-Methylbenzenesulfonate; Methyl 6-O-tosyl-α-D-glucopyranoside; Methyl 6-O-p-toluenesulfonyl-a-D-glucopyranose; NSC 170172. Grades: 98%. CAS No. 6619-9-6. Molecular formula: C14H20O8S. Mole weight: 348.37.
trans-4-Hydroxy-lomustine
trans-4-Hydroxy-lomustine is an impurity of lomustine which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine. Synonyms: 1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239717; trans-4-Hydroxy CCNU. Grades: > 95%. CAS No. 56239-24-8. Molecular formula: C9H16ClN3O3. Mole weight: 249.69.
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