Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Refametinib | Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor RDEA119 specifically inhibits mitogen-activated protein kinase kinase 1 (MAP2K1 or MAPK/ERK kinase 1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers. Synonyms: RDEA119; RDEA-119; RDEA 119; BAY 869766; BAY-69766; BAY869766; BAY 86 9766; BAY 86-9766; BAY86-9766; BAY 869766. Grades: >98%. CAS No. 923032-37-5. Molecular formula: C19H20F3IN2O5S. Mole weight: 572.338. |  |
| Refametinib Impurity 7 | Refametinib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1415582-04-5. Molecular formula: C20H18F3IN2O5S. Mole weight: 582.33. Catalog: APB1415582045. |  |
| Refametinib R enantiomer | Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1/2 in enzyme inhibition assays. It has been reported to inhibit MEK activity and inhibit anchorage-dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models. Synonyms: BAY 869766 R enantiomer; RDEA119 R enantiomer; BAY869766 R enantiomer; RDEA 119 R enantiomer; BAY-869766 R enantiomer; RDEA-119 R enantiomer. Grades: >98%. CAS No. 923032-38-6. Molecular formula: C19H20F3IN2O5S. Mole weight: 572.34. | |
Our database is helping our users find suppliers everyday.
