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| Product | Description | |
|---|---|---|
| Regorafenib Impurity 1 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C25H19F2N5O4. Mole weight: 491.46. |  |
| Regorafenib Impurity 2 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C21H16F4N4O3. Mole weight: 448.38. | |
| Regorafenib Impurity 27 | Regorafenib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68. Catalog: APB1333390569. |  |
| Regorafenib Impurity 3 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. | |
| Regorafenib Impurity 4 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C20H18FN5O3. Mole weight: 395.4. | |
| Regorafenib Impurity 5 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C27H22F2N6O5. Mole weight: 548.51. | |
| Regorafenib Impurity 6 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 6; Regorafenib metabolite M6; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic acid; ZU2HG2Y956; UNII-ZU2HG2Y956; 2-Pyridinecarboxylic acid, 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) -3-fluorophenoxy) -; 4- (4- ( (4-Chloro-3- (trifluoromethyl) phenyl) carbamoylamino) -3-fluoro-phenoxy) pyridine-2-carboxylic acid; 4-[4-[[4-chloro-3- (trifluoromethyl) phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxylic acid; SCHEMBL4609009; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy) picolinic acid. Grades: > 95%. CAS No. 1187945-05-6. Molecular formula: C20H12ClF4N3O4. Mole weight: 469.78. | |
| Regorafenib Impurity 62 | Regorafenib Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1855006-12-0. Molecular formula: C20H18FN5O3. Mole weight: 395.39. Catalog: APB1855006120. | |
| Regorafenib Impurity 7 | An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C36H24Cl2F7N5O5. Mole weight: 810.52. | |
| Regorafenib EP Impurity D | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4,4'-(((carbonylbis(azanediyl))bis(3-fluoro-4,1-phenylene))bis(oxy))bis(N-methylpicolinamide). CAS No. 2438857-80-6. Molecular formula: C27H22F2N6O5. Mole weight: 548.50. | |
| Regorafenib monohydrate impurity B [EP] | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 02; 4-(4-acetamido-3-fluorophenoxy)-N-methylpicolinamide. CAS No. 2141961-84-2. Molecular formula: C15H14FN3O3. Mole weight: 303.29. | |
| Regorafenib monohydrate impurity C [EP] | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpyridine-2-carboxamide; 4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide. CAS No. 1855006-12-0. Molecular formula: C20H18FN5O3. Mole weight: 395.39. | |
| 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Urea Impurity; Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(2-fluoro-4-hydroxyphenyl)-. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68. | |
| ethyl (2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 06. CAS No. 2514957-39-0. Molecular formula: C16H16FN3O4. Mole weight: 333.31. | |
| Regorafenib N-Beta-D-Glucuronide Sodium Salt | Regorafenib N-Beta-D-Glucuronide Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S,4S,5R,6R)-6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid Sodium Salt. IUPAC Name: sodium;(2S,3S,4S,5R,6R)-6-[4-chloro-N-[[2-fluoro-4-[[2-(methylcarbamoyl)-4-pyridyl]oxy]phenyl]carbamoyl]-3-(trifluoromethyl)anilino]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylate. Molecular formula: C27H22ClF4N4O9.Na. Mole weight: 680.92. Catalog: APS002935. SMILES: [Na+].CNC(=O)c1cc(Oc2ccc(NC(=O)N([C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)[O-])c4ccc(Cl)c(c4)C(F)(F)F)c(F)c2)ccn1. Format: Neat. | |
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