Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Relaxin H2 (human) | Relaxin H2 (human), a recombinant human relaxin targeting the RLN receptor, is a vasoactive peptide hormone with antifibrotic activity. Relaxin H2 is a pregnancy hormone with cardioprotective activity. It is the main storage and circulation subtype of relaxin peptide hormone in humans. Synonyms: Serelaxin; (Pyr-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys-OH)A (H-Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser-OH)B (Disulfide bridge: Cys10A-Cys15A, Cys11A-Cys11B, Cys24A-Cys23B); L-alpha-aspartyl-L-seryl-L-tryptophyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-valyl-L-isoleucyl-L-lysyl-L-leucyl-L-cysteinyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-valyl-L-arginyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-alanyl-L-isoleucyl-L-cysteinyl-glycyl-L-methionyl-L-seryl-L-threonyl-L-tryptophyl-L-serine (11->11'),(23->24')-bis(disulfide) compound with L-pyroglutamyl-L-leucyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-alanyl-L-asparagyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-valyl-glycyl-L-cysteinyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-L-leucyl-L-alanyl-L-arginyl-L-phenylalanyl-L-cysteine (10'->15')-disulfide; Human relaxin II. Grades: ≥95% by HPLC. CAS No. 99489-94-8. Molecular formula: C256H408N74O74S8. Mole weight: 5963.04. |  |
| Relaxin H3 (human) | Relaxin H3, a specific ligand for the leucine-rich repeat-containing G protein-coupled receptor LGR7, exerts anti-fibrosis effects through relaxin receptor RXFP1 and may enhance the collagen-inhibiting effect of relaxin H2. Synonyms: (H-Asp-Val-Leu-Ala-Gly-Leu-Ser-Ser-Ser-Cys-Cys-Lys-Trp-Gly-Cys-Ser-Lys-Ser-Glu-Ile-Ser-Ser-Leu-Cys-OH)A (H-Arg-Ala-Ala-Pro-Tyr-Gly-Val-Arg-Leu-Cys-Gly-Arg-Glu-Phe-Ile-Arg-Ala-Val-Ile-Phe-Thr-Cys-Gly-Gly-Ser-Arg-Trp-OH)B (Disulfide bridge: Cys10A-Cys15A, Cys11A-Cys10B, Cys24A-Cys22B). Grades: ≥95% by HPLC. CAS No. 1158181-62-4. Molecular formula: C237H374N70O69S6. Mole weight: 5500.31. | |
| RXFP1 Agonist (2-Isopropoxy-N- (2- (3- (trifluoro methyl sulfonyl) phenylcarbamoyl) phenyl) benzamide, LGR7 Agonist, Relaxin/Insulin-like Family Peptide Receptor 1 Agonist, Leucine-Rich Repeat-Containing GPCR 7 Agonist) | A cell-permeable 2-acetamido-N-phenylbenzamide that selectively activates human, but not mouse, LGR7/RXFP1-mediated cAMP induction (EC50 = 200nM in THP1) via allosteric interaction with the ECL3 region without competing against ECL2-mediated relaxin binding or affecting AVPR1B- or LGR8/RXFP2-mediated cAMP induction. Although shown to be ~150-fold and 500-fold less potent than relaxin (RLX), respectively, in VEGF mRNA induction and cellular impedance assays, pharmacokinetic studies reveal superior in vivo stability to RLX and in vivo bioavailability in mice via oral (Cmax/Tmax = 604nM/plasma/1h and 1026ng/g heart/1.5h; 30mg/kg) or intraperitoneal (Cmax/Tmax = 9.29uM/plasma/1h and 28.6uMol/kg heart/1h; 30mg/kg) administration with good aqueous solubility (7uM in PBS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| ML-290 | ML-290 is an allosteric agonist of relaxin family peptide receptor 1 (RXFP1). It increases cAMP accumulation and VEGF expression in cells that endogenously express human RXFP1. ML290 exhibits antifibrotic effects in liver fibrosis. Synonyms: ML 290; ML290; RXFP1 Agonist 8??; 2-[ (2-propan-2-yloxybenzoyl) amino]-N-[3- (trifluoromethylsulfonyl) phenyl]benzamide. Grades: ≥95%. CAS No. 1482500-76-4. Molecular formula: C24H21F3N2O5S. Mole weight: 506.5. | |
Our database is helping our users find suppliers everyday.
