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| Product | Description | |
|---|---|---|
| Remogliflozin | Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with K i s of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is the active form of Remogliflozin etabonate(HY-14945) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remogliflozin A. CAS No. 329045-45-6. Pack Sizes: 5 mg. Product ID: HY-13414. |  |
| Remogliflozin | Remogliflozin is a selective inhibitor of sodium-glucose transporter 2 (SGLT2) that promotes blood glucose to be eliminated through the urine. The prodrug Remoglifozin etabonate (GSK 189075) is converted into remogliflozin in vivo, and is suggested for the treatment of type II diabetes. Uses: The treatment of type ii diabetes. Synonyms: Remogliflozin A; Remogliflozin - GSK189074; GSK-189074; GSK 189074. (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxyoxane-3,4,5-triol. Grades: 99%. CAS No. 329045-45-6. Molecular formula: C23H34N2O7. Mole weight: 450.53. |  |
| Remogliflozin etabonate | Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with K i values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate is a proagent based on benzylpyrazole glucoside and is metabolized to its active form, Remogliflozin, in the body. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK189075. CAS No. 442201-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14945. | |
| Remogliflozin etabonate | Remogliflozin etabonat, pro-drug of remogliflozin, is a SGLT2 inhibitor under development for the treatment of type 2 diabetes. Remogliflozin etabonate is a pro-drug of remogliflozin, inhibits the sodium-glucose transport proteins (SGLT), which are responsible for glucose reabsorption in the kidney. Uses: Sglt2 inhibitor. Synonyms: GSK189075A; GSK-189075A; GSK 189075A; GSK189075; GSK-189075; GSK 189075; Remogliflozin etabonate.beta-D-Glucopyranoside, 5-methyl-4-((4-(1-methylethoxy)phenyl)methyl)-1-(1-methylethyl)-1H-pyrazol-3-yl, 6-(ethyl carbonate). Grades: ≥98%. CAS No. 442201-24-3. Molecular formula: C26H38N2O9. Mole weight: 522.59. | |
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