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| Product | Description | |
|---|---|---|
| Rencofilstat | Rencofilstat (CRV431) is a pan-cyclophilin inhibitor with IC 50 values of 2.5 nM, 3.1 nM, 2.8 nM, 7.3 nM for Cyp A, CypB, Cyp D and Cyp G, respectively. Rencofilstat reduces fibrosis and tumor growth in models of chronic liver disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRV431. CAS No. 1383420-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135644. |  |
| Rencofilstat | Rencofilstat is a cyclophilin inhibitor. Synonyms: CRV431; CRV-431; CRV 431; 6-[(2S,3R,4R)-10-acetamido-3-hydroxy-4-methyl-2-(methylamino)decanoic acid]-8-(N-methyl-D-alanine)cyclosporin A; 1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R)-10-acetamido-3-hydroxy-N,4-dimethyl-L-2-aminodecanoyl-L-2-aminobutanoyl-N-methyl-D-alanyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]; N-((7R, 8R)-8-((2S, 5S, 8R, 11S, 14S, 17S, 20S, 23R, 26S, 29S, 32S)-5-Ethyl-11, 17, 26, 29-tetraisobutyl-14, 32-diisopropyl-1, 7, 8, 10, 16, 20, 23, 25, 28, 31-decamethyl-3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33-undecaoxo-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecaazacyclotritriacontan-2-yl)-8-hydroxy-7-methyloctyl)acetamide. CAS No. 1383420-08-3. Molecular formula: C67H122N12O13. Mole weight: 1303.8. |  |
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