Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Reparixin | Reparixin is an inhibitor of CXCL8 receptor, and also inhibits CXCR1 and CXCR2 activation. Synonyms: (R) -2- (4-isobutylphenyl) propionylmethanesulfonamide; 2- (4-isobutylphenyl) propionylmethanesulfonamide; repertaxin. Grades: 98%. CAS No. 266359-83-5. Molecular formula: C14H21NO3S. Mole weight: 283.39. |  |
| Reparixin | Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC 50 s of 1 and 100 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Repertaxin; DF 1681Y. CAS No. 266359-83-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15251. |  |
| Reparixin L-lysine salt | The efficacy of RPX (tested in a wide range of concentrations (1-1000 nM)) was lower in cells expressing Ile43Val CXCR1 mutant (IC50 values of 0.0056 and 0.08 uM for CXCR1 weight and CXCR1 Ile43Val, respectively). Treatment with reparixin significantly counteracts secondary degeneration by reducing oligodendrocyte apoptosis, migration to the injury site of neutrophils and ED-1-positive cells. The best beneficial outcome of reparixin treatment required 7-day administration either by i.p. route (15 mg/kg) or subcutaneous infusion via osmotic pumps (10 mg/kg), reaching a steady blood level of 8 microg/ml. Reparixin effectively decreased systolic blood pressure and increased the blood flow. The thoracic aorta wall thickness was significantly decreased in SHR-R compared to SHR-N. Pre-treatment with reparixin reduced the motor deficits observed in this model of ischemia and reperfusion. Myeloperoxidase activity and IL-iβ were reduced in the reparixin-treated group. Histological analysis revealed that ischemic injury was also attenuated by reparixin pre-treatment. Synonyms: Repertaxin L-lysine salt. Grades: >98%. CAS No. 266359-93-7. Molecular formula: C20H35N3O5S. Mole weight: 429.57. | |
Our database is helping our users find suppliers everyday.
