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| Product | Description | |
|---|---|---|
| Resomelagon | Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC 1 and MC 3. Resomelagon induces ERK1/2 phosphorylation and Ca 2+ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP1189. CAS No. 1809420-71-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147301. |  |
| Resomelagon acetate | Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC 1 and MC 3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca 2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP1189 acetate. CAS No. 1809420-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147301A. | |
| AP 1189 | AP 1189 exhibits biased agonistic activity towards the melanocortin 1 and melanocortin 3 receptors. Synonyms: Hydrazinecarboximidamide, 2-[(2E)-3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-2-propen-1-ylidene]-, acetate (1:1), (2E)-; AP1189; AP-1189; Resomelagon acetate; (E)-2-((E)-3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidene)hydrazine-1-carboximidamide acetate. Grades: ≥95%. CAS No. 1809420-72-1. Molecular formula: C14H14N6O2.C2H4O2. Mole weight: 358.35. |  |
| AP1189 acetate | AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ~3-fold. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AP-1189; AP 1189; AP1189; AP1189 acetate. Product Category: Agonists. Appearance: Solid powder. CAS No. 959850-74-9. Molecular formula: C16H18N6O4. Mole weight: 358.36. Purity: >98%. IUPACName: (E)-N-[trans-3-{1-(2-Nitrophenyl)-1H-pyrrol-2-yl} allylidenamino]guanidinium acetate. Canonical SMILES: NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O. Product ID: ACM959850749. Alfa Chemistry ISO 9001:2015 Certified. Categories: Resomelagon acetate. |  |
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