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| Product | Description | |
|---|---|---|
| Retapamulin | 250mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C30H47NO4S. CAS No. 224452-66-8. Prepack ID 89984827-250mg. Molecular Weight 517.76. See USA prepack pricing. |  |
| Retapamulin | Retapamulin, also known as SB-275833, is a newer topical agent of pleuromutilin class approved by the Food and Drug Administration for treatment of impetigo in children. It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram-positive bacteria found in skin infections including Staphylococcus aureus strains. The drug is safe owing to low systemic absorption and has only minimal side-effect of local irritation at the site of application. Group: Others. Alternative Names: SB-275833; SB 275833; SB275833; Retapamulin, brand names Altabax and Altargo. CAS No. 224452-66-8. Molecular formula: C30H47NO4S. Mole weight: 517.76. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (3aR,4S,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)acetate. Canonical SMILES: O=C (O[C@@H]1C[C@] (C=C) (C)[C@@H] (O)[C@H] (C)[C@]2 (CCC3=O)[C@]3 ([H])[C@]1 (C)[C@H] (C)CC2)CS[C@@H]4C[C@@] (N5C) ([H])CC[C@@]5 ([H])C4. Catalog: ACM224452668. |  |
| Retapamulin | Retapamulin is a pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation. It has activity against staphylococcal, streptococcal, and anaerobic Gram-positive bacteria. Group: Biochemicals. Alternative Names: [(3-exo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]acetic Acid; [(3aS, 4R, 5S, 6S, 8R, 9R, 9aR, 10R)-6-ethenyldecahydro-5-hydroxy-4, 6, 9, 10-tetramethyl-1-oxo-3a, 9-propano-3aH-cyclopentacycloocten-8-yl Ester; Altabax; Altargo; Mutilin; 14-(exo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)acetate. Grades: Highly Purified. CAS No. 224452-66-8. Pack Sizes: 1g, 5g. Molecular Formula: C??H??NO?S, Molecular Weight: 517.76. US Biological Life Sciences. |  Worldwide |
| Retapamulin | Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM. Retapamulin can be used in researches of atopic dermatitis and prostate cancer [1] [2] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-275833. CAS No. 224452-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17010. |  |
| Retapamulin Impuirty 1 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H47NO5S. Mole weight: 533.78. |  |
| Retapamulin Impuirty 2 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C16H26N2S2. Mole weight: 310.53. | |
| Retapamulin Impuirty 3 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C31H49NO4S2. Mole weight: 563.87. | |
| Retapamulin Impuirty 4 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C38H58N2O4S3. Mole weight: 703.09. | |
| Retapamulin Impuirty 5 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C39H60N2O4S3. Mole weight: 717.12. | |
| Retapamulin Impuirty 6 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H45NO4S. Mole weight: 515.76. | |
| Retapamulin Impurity 10 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H47NO4S. Mole weight: 517.78. | |
| Retapamulin Impurity 11 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H47NO4S. Mole weight: 517.78. | |
| Retapamulin Impurity 12 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H45NO3S. Mole weight: 499.76. | |
| Retapamulin Impurity 7 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. CAS No. 35136-87-9. Molecular formula: C10H18O3S. Mole weight: 218.32. | |
| Retapamulin Impurity 8 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Synonyms: (3-endo)-8-Methyl-8-Azabicyclo[3.2.1]octane-3-thiol Hydrochloride;Tropine-3-thiol Hydrochloride. Grades: > 95%. Molecular formula: C8H15NS. Mole weight: 157.28. | |
| Retapamulin Impurity 9 | An impurity of Retapamulin. Retapamulin is a topical antibiotic. It can be used for the treatment of bacterial skin infections such as impetigo. Grades: > 95%. Molecular formula: C30H45NO4S. Mole weight: 515.76. | |
| exo-Tropine-3-thiol Hydrochloride | exo-Tropine-3-thiol Hydrochloride is used in the synthesis of Retapamulin, which is a topical antibiotic used for the topical treatment of impetigo caused by Staphylococcus aureus (methicillin-susceptible only) or Streptococcus pyogenes. Synonyms: 8-Azabicyclo[3.2.1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)-; (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride (1:1). CAS No. 1141886-66-9. Molecular formula: C8H15NS.HCl. Mole weight: 193.74. | |
| Pleuromutilin 22-Mesylate | Pleuromutilin 22-Mesylate is a derivative of Pleuromutilin, which is an antibiotic produced by the basidiomycetes Pleurotus mutilus and used for the synthesis of Retapamulin. Synonyms: [3aS-(3aα, 4β, 5α, 6α, 8β, 9α, 9aβ, 10S*)]-6-Ethenyldecahydro-5-hydroxy-4, 6, 9, 10-tetramethyl-1-oxo-3a, 9-propano-3aH-cyclopentacycloocten-8-yl Ester [(Methylsulfonyl)oxy]acetic Acid; 3a,9-Propano-3aH-cyclopentacyclooctene, acetic acid deriv; pleuromutilin methanesulfonate; pleuromutilin mesylate; PLM-mesylate; 2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester. Grades: ≥95%. CAS No. 60924-38-1. Molecular formula: C23H36O7S. Mole weight: 456.59. | |
| Pleuromutilin (Drosophilin B, Antibiotic A 40104C) | Pleuromutilin is a diterpene produced by several species of basidomycetes, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 125-65-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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