Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Retaspimycin | Retaspimycin (IPI 504) is a small-molecule inhibitor of heat shock protein 90 (Hsp90) with antiproliferative and antineoplastic activities. Retaspimycin binds to and inhibits the cytosolic chaperone functions of Hsp90, which maintains the stability and functional shape of many oncogenic signaling proteins and may be overexpressed or overactive in tumor cells. Retaspimycin-mediated inhibition of Hsp90 promotes the proteasomal degradation of oncogenic signaling proteins in susceptible tumor cell populations, which may result in the induction of apoptosis. Synonyms: IPI-504; IPI 504; IPI504. Grades: >98%. CAS No. 857402-23-4. Molecular formula: C31H45N3O8. Mole weight: 587.70. |  |
| Retaspimycin Hydrochloride | Retaspimycin HCl is the hydrochloride salt of a small-molecule inhibitor of Hsp90 with antineoplastic and antiproliferative activities. Retaspimycin binds to and inhibits the cytosolic chaperone functions of Hsp90, which maintains the stability and functional shape of many oncogenic signaling proteins and has the possibililty to be overexpressed or overactive in tumor cells. Retaspimycin-mediated inhibition of Hsp90 promotes the proteasomal degradation of oncogenic signaling proteins in susceptible tumor cell populations, which may lead to the induction of apoptosis. Synonyms: retaspimycin hydrochloride; Retaspimycin HCl; IPI-504; 857402-63-2; IPI-504 HYDROCHLORIDE; CHEBI:71956; IPI 504; Retaspimycin hydrochloride [USAN]; Retaspimycin (Hydrochloride); 928Q33Q049; 857402-63-2 (HCl); [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6,20,22-trihydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16-oxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(22),8,12,14,18,20-hexaen-10-yl] carbamate; hydrochloride; Retaspimycin hydrochloride (USAN); 17-Allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride. Grades: >95%. CAS No. 857402-63-2. Molecular formula: C31H48ClN3O8. Mole weight: 626.17. | |
| Retaspimycin Hydrochloride | Retaspimycin Hydrochloride is a potent inhibitor of Hsp90 with EC 50 s of 119 nM for both Hsp90 and Grp9. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-504. CAS No. 857402-63-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10210. |  |
Our database is helping our users find suppliers everyday.
