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RETRA is a mutant p53-dependent activator of p73 that suppresses mutant p53-bearing cancer cells. RETRA increases the expression level of p73, and a release of p73 from the blocking complex with mutant p53, which produces tumor-suppressor effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1036069-26-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108636.
RETRA hydrochloride
RETRA hydrochloride, an antitumor agent, inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and in vivo (IC50 = 4 μM). Synonyms: 2-[(4,5-Dihydro-2-thiazolyl)thio]-1-(3,4-dihydroxyphenyl)ethanone hydrochloride. Grades: ≥99% by HPLC. CAS No. 1173023-52-3. Molecular formula: C11N11NO3S2.HCl. Mole weight: 305.8.
RETRA hydrochloride
RETRA hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1173023-52-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one inhibits neurite outgrowth and causes neurite retraction in PC12 cells independently of soluble guanylyl cyclase. Group: Biochemicals. Alternative Names: ODQ. Grades: Highly Purified. CAS No. 41443-28-1. Pack Sizes: 50mg. US Biological Life Sciences.
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1-Palmitoyl lysophosphatidic acid
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Synonyms: 1-Palmitoyl LPA; 1-Palmitoylglycerol 3-phosphate. Grades: ≥98%. CAS No. 22002-85-3. Molecular formula: C19H39O7P. Mole weight: 410.5.
Ingenol
Ingenol, the analogue of Ingenol 3-Angelate found in the seeds of Euphorbia lathyris L, is an extremely weak PKC (protein kinase C) activator ( Ki=30μM, ED50=27μM, in vitro). Ingenol has anti-tumor activity when used topically for the treatment of actin. Uses: Anticancer. Synonyms: 1A,2,5,5A,6,9,10,10A OCTAHYDRO-5,5A,6-TRIHYDROXY4(HYDROXYMETHYL)1,1,7,9-TETRAMETHYL1H-2,8 AMETHANOCYCLOPENTA [A]CYCLOPROPA [E]CYCLODECEN-11 ONE;1 ALPHA,2,5,5 ALPHA,6,9,10,10 ALPHA-OCTAHYDRO-5,5 ALPHA,6-TRIHYDROXY-4-HYDROXYMETHYL-1,1,7,9-RETRAMETHYL-1H-2,8 A. Grades: >98%. CAS No. 30220-46-3. Molecular formula: C20H28O5. Mole weight: 348.44.
Xylanase is the name given to a class of enzymes which degrade the linear polysaccharide beta-1,4-xylan into xylose, thus breaking down hemicellulose, one of the major components of plant cell walls. As such, it plays a major role in micro-organisms thriving on plant sources for the degradation of plant matter into usable nutrients. Xylanases are produced by fungi, bacteria, yeast, marine algae, protozoans, snails, crustaceans, insect, seeds, etc., (mammals do not produce xylanases). Xylanase which made from the best strain of bacillus subtilis. it is a kind of purified endo-bacteria-xylanase. it can be applied in the flour treatment for bread powder and steam brea...and chewy. 2) in the storage of bread, the appropriate xylanase can retrad bread staling, improve the water holding capacity of the bread and optimize the gluten network, thereby, preventing water loss and re-allocate, stabilize the organizational structure of the bread. Group: Enzymes. Synonyms: EC 3.2.1.8; endo-(1?4)-β-xylan 4-xylanohydrolase; endo-1,4-xylanase; xylanase; β-1,4-xylanase; endo-1,4-xylanase; endo-β-1,4-xylanase; endo-1,4-β-D-xylanase; 1,4-β-xylan xylanohydrolase; β-xylanase; β-1,4-xylan xylanohydrolase; endo-1,4-β-xylanase; β-D-xylanase; endo-1,4-β-xylanase. Enzyme Commission Number: EC 3.2.1.8. CAS
Potassium Pyruvate
Pyruvic Acid Potassium Salt is an intermdiate in sugar metabolism and enzymatic carbohydrate degredation. It is converted by carboxylase into acetaldehyde and CO2. In muscle, it is reduced to lactic acid during exertion, then reoxidized and partly retransformed to glycogen upon resting. When present in culture medium, it improves coliform recovery. It has been shown to be involved in a mitochondrial oxidant-activated metabolic regulatory pathway. It has also been shown to be involved in plant respiratory regulation. Group: Biochemicals. Alternative Names: Pyruvic Acid Potassium Salt. Grades: Highly Purified. CAS No. 4151-33-1. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C3H3KO3, Molecular Weight: 126.15. US Biological Life Sciences.
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Sodium Pyruvate (Pyruvic Acid Sodium Salt)
Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease. Used in culture broth and media as an energy source for propagating cells. Group: Biochemicals. Alternative Names: 2-Oxopropanoic Acid Sodium Salt; Sodium Pyruvate; Sodium α-Ketopropionate. Grades: Cell Culture Grade. CAS No. 113-24-6. Pack Sizes: 100g, 500g, 1Kg, 2.5Kg. Molecular Formula: C3H3O3Na, Molecular Weight: 110. US Biological Life Sciences.
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