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| Product | Description | |
|---|---|---|
| Reversin 121 | Reversin 121 is a selective P-glycoprotein multidrug transporter (MDR1) inhibitor with Kd value of 77 nM. Synonyms: reversin 121; 174630-04-7; CHEMBL221390; tert-butyl (2S) -2-[[ (2S) -2-[ (2-methylpropan-2-yl) oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6- (phenylmethoxycarbonylamino) hexanoate; Boc-Asp(Obzl)-Lys(Z)-OtBu; BDBM50326927; DB14072; HY-125486; Reversin 121, >=97% (HPLC), powder; CS-0091919; (S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)-4-oxobutanamido)-6-(benzyloxycarbonylamino)hexanoate; tert-Butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate. Grades: ≥98%. CAS No. 174630-04-7. Molecular formula: C34H47N3O9. Mole weight: 641.8. |  |
| Reversine | Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC 50 s of 400, 500 and 400 nM for Aurora A , Aurora B and Aurora C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 656820-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14711. |  |
| Reversine | Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Synonyms: Reversine; 656820-32-5; 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; CHEMBL188343; CHEBI:70723; C21H27N7O; N6-cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine; N6-cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine; Z499CLJ023; MFCD07784513; N~6~-Cyclohexyl-N~2~-(4-Morpholin-4-Ylphenyl)-9h-Purine-2,6-Diamine; N(6)-cyclohexyl-N(2)-[4-(morpholin-4-yl)phenyl]-9H-purine-2,6-diamine; 2vgo. CAS No. 656820-32-5. Molecular formula: C21H27N7O. Mole weight: 393.49. | |
| Reversine (2-(4-Morpholinoanilino)-6-cyclohexylaminopurine) | A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66uM) and an aurora kinase inhibitor (IC??'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 656820-32-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Retreversine | Reversine is a 2,6-disubstituted purine derivative used for stem cell differentiation. It also has the role as a potent inhibitor of the mitotic kinase Mps1. Synonyms: N2-Cyclohexyl-N6-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine. Grades: ≥98%. CAS No. 1028332-91-3. Molecular formula: C21H27N7O. Mole weight: 393.5. | |
| CAY10498 | The A1, A2A, A2B, and A3 adenosine receptors (ARs) are ubiquitous G protein-coupled receptors. A3 AR antagonists are of interest as therapeutic agents in glaucoma agents and inflammation. CAY10498 is a potent and selective Adenosine A3-R (A3 AR) antagonist exhibiting a Ki of 37 nM. It is 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively. CAY10498 is also a structural analog of reversine, which is a dedifferentiation agent of embryonic progenitor cells. Synonyms: 2-phenyl-amino-N6-endo-norbornyladenine. Grades: ≥95%. CAS No. 863202-33-9. Molecular formula: C18H20N6. Mole weight: 320.4. | |
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