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| Product | Description | |
|---|---|---|
| RG108 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| RG108 | RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Synonyms: N-Phthalyl-L-tryptophan; RG-108; (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid. Grades: >98%. CAS No. 48208-26-0. Molecular formula: C19H14N2O4. Mole weight: 334.33. |  |
| RG108 | RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Phthalyl-L-tryptophan. CAS No. 48208-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13642. |  |
| RG 108 (N-Phthalyl-L-tryptophan) | A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. Group: Biochemicals. Grades: Highly Purified. CAS No. 48208-26-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
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