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Rhosin hydrochloride Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro. Also induces neurite outgrowth in synergy with NGF. Synonyms: Rhosin hydrochloride. Grades: >98%. CAS No. 1281870-42-5. Molecular formula: C20H19ClN6O. Mole weight: 394.86. BOC Sciences 11
Rhosin hydrochloride Rhosin hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 1281870-42-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H18N6O HCl 1.25 H2O, Molecular Weight: 417.38. US Biological Life Sciences. USBiological 5
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