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| Product | Description | |
|---|---|---|
| Ribociclib succinate | Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC 50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LEE011 succinate. CAS No. 1374639-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15777B. |  |
| Ribociclib succinate hydrate | Ribociclib succinate hydrate (LEE011 succinate hydrate) is a highly specific CDK4/6 inhibitor with IC 50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LEE011 succinate hydrate. CAS No. 1374639-79-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15777C. | |
| LEE011 succinate | LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. Synonyms: Ribociclib succinate; LEE 011 succinate; LEE-011 succinate. Grades: >98%. CAS No. 1374639-75-4. Molecular formula: C27H36N8O5. Mole weight: 552.63. |  |
| LEE011 succinate hydrate | LEE011 succinate hydrate is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. Synonyms: Ribociclib succinate hydrate; LEE 011 succinate hydrate; LEE-011 succinate hydrate. Grades: >98%. CAS No. 1374639-79-8. Molecular formula: C27H38N8O6X. Mole weight: 570.64. | |
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