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| Product | Description | |
|---|---|---|
| Rigosertib sodium | Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle [1] [2]. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC 50 of 9 nM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ON-01910 sodium. CAS No. 592542-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12037. |  |
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