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| Product | Description | |
|---|---|---|
| Riociguat | Riocguat is used in the treatment for pulmonary hypertension. Group: Biochemicals. Alternative Names: N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamic Acid Methyl Ester; [4, 6-Diamino-2- [1- [ (2-fluorophenyl) methyl] -1H-pyrazolo [3, 4-b] pyridin-3-yl] -5-pyrimidinyl] methylcarbamic Acid Methyl Ester; BAY 63-2521; BAY 632521; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate. Grades: Highly Purified. CAS No. 625115-55-1. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Riociguat | Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators. Synonyms: BAY 63-2521; BAY63-2521; BAY632521; Riociguat; Brand name: Adempas. Grades: 0.99. CAS No. 625115-55-1. Molecular formula: C20H19FN8O2. Mole weight: 422.424. |  |
| Riociguat | Riociguat is an oral stimulator of soluble guanylate cyclase ( sGC ) used in the treatment of pulmonary hypertension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 632521. CAS No. 625115-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14779. |  |
| Riociguat | Riociguat. Uses: For analytical and research use. Group: Impurity standards. CAS No. 625115-55-1. Molecular Formula: C20H19FN8O2. Mole Weight: 422.42. Catalog: APB625115551. |  |
| Riociguat Impurity 1 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)(methyl)carbamate; Riociguat Impurity I. Grades: > 95%. Molecular formula: C21H21FN8O2. Mole weight: 436.45. | |
| Riociguat Impurity 10 | Riociguat Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 256499-19-1. Molecular Formula: C14H13ClFN5. Mole Weight: 305.74. Catalog: APB256499191. | |
| Riociguat Impurity 11 | Riociguat Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1361569-18-7. Molecular Formula: C19H15FN8O. Mole Weight: 390.38. Catalog: APB1361569187. | |
| Riociguat Impurity 12 | Riociguat Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1361569-23-4. Molecular Formula: C20H17FN8O. Mole Weight: 404.41. Catalog: APB1361569234. | |
| Riociguat Impurity 13 | Riociguat Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1361569-10-9. Molecular Formula: C18H13FN8O. Mole Weight: 376.36. Catalog: APB1361569109. | |
| Riociguat Impurity 14 | Riociguat Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 625115-54-0. Molecular Formula: C22H23FN8O2. Mole Weight: 450.48. Catalog: APB625115540. | |
| Riociguat Impurity 15 | Riociguat Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H20FN9O3. Mole Weight: 465.45. Catalog: APB09587. | |
| Riociguat Impurity 16 | Riociguat Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H16FN9O. Mole Weight: 393.39. Catalog: APB09588. | |
| Riociguat Impurity 2 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboximidic acid methyl ester. Grades: > 95%. CAS No. 304874-06-4. Molecular formula: C15H13FN4O. Mole weight: 284.3. | |
| Riociguat Impurity 2 | Riociguat Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H20N8O2. Mole Weight: 404.43. Catalog: APB09584. | |
| Riociguat Impurity 3 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Grades: > 95%. Molecular formula: C23H20FN9. Mole weight: 441.47. | |
| Riociguat Impurity 3 | Riociguat Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H19FN8O2. Mole Weight: 422.42. Catalog: APB09585. | |
| Riociguat Impurity 4 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Dimethyl (6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5-diyl)dicarbamate. Grades: > 95%. Molecular formula: C21H19FN8O4. Mole weight: 466.44. | |
| Riociguat Impurity 4 | Riociguat Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 625115-52-8. Molecular Formula: C19H17FN8O2. Mole Weight: 408.4. Catalog: APB625115528. | |
| Riociguat Impurity 5 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-(methylamino)pyrimidin-5-yl)carbamate. Grades: > 95%. Molecular formula: C20H19FN8O2. Mole weight: 422.43. | |
| Riociguat Impurity 5 | Riociguat Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H21FN8O2. Mole Weight: 436.45. Catalog: APB09586. | |
| Riociguat Impurity 6 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-N5-methyl-4,5,6-pyrimidinetriamine. Grades: > 95%. CAS No. 1702271-98-4. Molecular formula: C18H17FN8. Mole weight: 364.39. | |
| Riociguat Impurity 6 | Riociguat Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2708578-77-0. Molecular Formula: C21H19FN8O4. Mole Weight: 466.43. Catalog: APB2708578770. | |
| Riociguat Impurity 7 | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Methyl (4-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-6-((methoxycarbonyl)amino)pyrimidin-5-yl)(methyl)carbamate. Grades: > 95%. Molecular formula: C22H21FN8O4. Mole weight: 480.46. | |
| Riociguat Impurity 7 | Riociguat Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1702271-98-4. Molecular Formula: C18H17FN8. Mole Weight: 364.39. Catalog: APB1702271984. | |
| Riociguat Impurity 8 | Riociguat Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2518331-19-4. Molecular Formula: C22H21FN8O4. Mole Weight: 480.46. Catalog: APB2518331194. | |
| Riociguat Impurity 9 | Riociguat Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2514697-53-9. Molecular Formula: C20H19FN8O2. Mole Weight: 422.42. Catalog: APB2514697539. | |
| Riociguat M1 Glucuronide | An impurirty of Riociguat ,Riociguat is used in the treatment for pulmonary hypertension. Grades: > 95%. Molecular formula: C25H25FN8O8. Mole weight: 584.53. | |
| 2-Desfluoro-3-fluoro-riociguat | 2-Desfluoro-3-fluoro-riociguat is an impurity of Riociguat (R520000), which is used in the treatment for pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C20H19FN8O2, Molecular Weight: 422.42. US Biological Life Sciences. | Worldwide |
| 2-Desfluoro-4-fluoro-riociguat | 2-Desfluoro-4-fluoro-riociguat is an impurity of Riociguat (R520000), which is used in the treatment for pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C20H19FN8O2, Molecular Weight: 422.42. US Biological Life Sciences. | Worldwide |
| 2-Desfluoro-riociguat | 2-Desfluoro-riociguat is an impurity of Riociguat (R520000), which is used in the treatment for pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C20H20N8O2, Molecular Weight: 404.43. US Biological Life Sciences. | Worldwide |
| 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-; Riociguat Impurity 21. CAS No. 256376-65-5. Molecular formula: C14H9FN4. Mole weight: 252.25. | |
| 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 1-[(2-fluorophenyl)methyl]-; Riociguat Impurity 19. CAS No. 256376-62-2. Molecular formula: C14H11FN4O. Mole weight: 270.26. | |
| 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 256499-19-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C14H13ClFN5. US Biological Life Sciences. | Worldwide |
| 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 20. CAS No. 956011-26-0. Molecular formula: C14H10FN3O2. Mole weight: 271.25. | |
| 1-(3-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 24. CAS No. 2101651-50-5. Molecular formula: C14H12FN5. Mole weight: 269.28. | |
| 2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-N5,N5-dimethylpyrimidine-4,5,6-triamine | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 18. CAS No. 1169770-52-8. Molecular formula: C19H19FN8. Mole weight: 378.41. | |
| 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-N5-methyl-4,5,6-pyrimidinetriamine | 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-N5-methyl-4,5,6-pyrimidinetriamine is an impurity of Riociguat (R520000); a compound used in the treatment of pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 1702271-98-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H17FN8, Molecular Weight: 364.38. US Biological Life Sciences. | Worldwide |
| 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dihydro-8H-purin-8-one | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 13; 6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one. CAS No. 1361569-10-9. Molecular formula: C18H13FN8O. Mole weight: 376.35. | |
| 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7,9-dihydro-8H-purin-8-one | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 7,9-Dimethyl-7,9-dihydro-8H-purin-8-one, 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-; Riociguat Impurity 12. Grades: 99% by HPLC. CAS No. 1361569-23-4. Molecular formula: C20H17FN8O. Mole weight: 404.40. | |
| 6-amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7-methyl-7,9-dihydro-8H-purin-8-one | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: 8h-purin-8-one, 6-amino-2-[1-[(2-fluorophenyl)methyl]-1h-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-7-methyl-; Methyl-dihydropurinone; Riociguat Impurity 11. CAS No. 1361569-18-7. Molecular formula: C19H15FN8O. Mole weight: 390.37. | |
| Ethyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: [4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]methylcarbamic acid ethyl ester; Riociguat Impurity 16. CAS No. 625115-53-9. Molecular formula: C21H21FN8O2. Mole weight: 436.44. | |
| Isopropyl(4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(methyl)carbamate | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: [4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]methylcarbamic acid 1-methylethyl ester; Riociguat Impurity 14. CAS No. 625115-54-0. Molecular formula: C22H23FN8O2. Mole weight: 450.47. | |
| methyl (4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)(ethyl)carbamate | An impurity of Riociguat. Riociguat is used in the treatment for pulmonary hypertension. Synonyms: Riociguat Impurity 27; Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-ethyl-, methyl ester. CAS No. 1361570-27-5. Molecular formula: C21H21FN8O2. Mole weight: 436.44. | |
| Nelociguat | Nelociguat is a soluble guanylate cyclase stimulator (sGC stimulator), which is a key enzyme in the nitric oxide (NO) signalling pathway. It is used for the treatment of pulmonary hypertension. It promotes vasodilation and inhibits smooth muscle proliferation, leukocyte recruitment, platelet aggregation and vascular remodelling through a number of downstream mechanisms. It was also used for erectile dysfunction and heart failure. It was developed by Bayer and was in clinic phase 2 trials with no progress. Uses: Nelociguat is used for the treatment of pulmonary hypertension. it was also used for erectile dysfunction and heart failure. Synonyms: BAY60-4552; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate; Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-, methyl ester; N-Desmethyl Riociguat. Grades: 98%. CAS No. 625115-52-8. Molecular formula: C19H17FN8O2. Mole weight: 408.39. | |
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