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| Product | Description | |
|---|---|---|
| Ripasudil | Ripasudil (K-115) is a specific inhibitor of ROCK , with IC 50 s of 19 and 51 nM for ROCK2 and ROCK1 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-115. CAS No. 887375-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15685. |  |
| Ripasudil (K-115) | Ripasudil is a potent ROCK inhibitor with IC50 values of 51 nM and 19 nM for ROCK1 and ROCK2, respectively. It has been used in eye drops for the treatment of corneal endothelial injuries. Synonyms: K-115; 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrate hydrochloride. Grades: >98%. CAS No. 887375-67-9. Molecular formula: C15H23ClFN3O4S. Mole weight: 395.88. |  |
| K-115 | K-115, also called as Ripasudil or Glanatec, a selective ROCK inhibitor (IC50 =31 nM), is a promising emerging antiglaucoma drug, and was thus approved by the Japanese administrative authority in 2014. Synonyms: 4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinolineGlanatecK-115; K 115; K115K115 compoundripasudil. CAS No. 223645-67-8. Molecular formula: C15H18FN3O2S. Mole weight: 323.39. | |
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