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| Product | Description | |
|---|---|---|
| Rodatristat | Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC 50 s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5417. CAS No. 1673568-73-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120083. |  |
| Rodatristat ethyl | Rodatristat ethyl is a tryptophan hydroxylase 1 (TPH1) inhibitor, which reduces 5-HT levels and significantly reduces pulmonary hypertension (PAH). Synonyms: KAR5585; KAR-5585. Grades: ≥98% by HPLC. CAS No. 1673571-51-1. Molecular formula: C29H31ClF3N5O3. Mole weight: 590. |  |
| Rodatristat ethyl | Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5585. CAS No. 1673571-51-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101124. | |
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