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| Product | Description | |
|---|---|---|
| Rogaratinib | Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100019. |  |
| Rogaratinib | Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Synonyms: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Molecular formula: C23H26N6O3S. Mole weight: 466.6. |  |
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