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| Product | Description | |
|---|---|---|
| Rolapitant | Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. |  |
| Rolapitant | Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751. |  |
| Rolapitant | Rolapitant. Uses: For analytical and research use. Group: Impurity standards. CAS No. 552292-08-7. Molecular Formula: C25H26F6N2O2. Mole Weight: 500.49. Catalog: APB552292087. |  |
| Rolapitant (1R,2R,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453123; EX-A1288F; Rolapitant (1R,2R,3R)-Isomer; FIVSJYGQAIEMOC-XARZLDAJSA-N; (5R, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-26-0. Grades: > 95%. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1R,2R,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453121; EX-A1288E; Rolapitant (1R,2R,3S)-Isomer; FIVSJYGQAIEMOC-AVIJNYRZSA-N; (5S, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-25-9. Grades: > 95%. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1R,2S,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL12679453; EX-A1288G; Rolapitant (1R,2S,3R)-Isomer; FIVSJYGQAIEMOC-UZFJHSOTSA-N; (5R, 8S) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 552292-73-6. Grades: > 95%. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2R,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Grades: > 95%. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2R,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453127; EX-A1288D; Rolapitant (1S,2R,3S)-Isomer; FIVSJYGQAIEMOC-FNVCAUGXSA-N; (5S, 8R) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-28-2. Grades: > 95%. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2S,3R)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: Rolapitant (1S,2S,3R)-Isomer. Grades: > 95%. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant (1S,2S,3S)-Isomer | An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453126; EX-A1288H; Rolapitant (1S,2S,3S)-Isomer; FIVSJYGQAIEMOC-PBNUPURSSA-N; HMS3750I21; (5S, 8S) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-27-1. Grades: > 95%. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant HCl hydrate | Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and late-phase CINV during the first 120 hours post-chemotherapy. Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[4. 5]decan-2-one hydrochloride.; SCH619734 SCH-619734; SCH 619734; Rolapitant HCl; Rolapitant hydrochloride, Rolapitant, brand name: Varubi. CAS No. 914462-92-3. Molecular formula: C25H26F6N2O2.ClH.H2O. Mole weight: 554.95. | |
| Rolapitant hydrochloride hydrate | Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734 hydrochloride hydrate. CAS No. 914462-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16436. | |
| Rolapitant Impurity 1 | Rolapitant Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H22D4F6N2O2. Mole Weight: 504.51. Catalog: APB11169. | |
| Rolapitant Impurity 4 | Rolapitant Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 552292-73-6. Molecular Formula: C25H26F6N2O2. Mole Weight: 500.49. Catalog: APB552292736. | |
| (2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate | (2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting. Group: Biochemicals. Grades: Highly Purified. CAS No. 205654-80-4. Pack Sizes: 250mg, 1g. Molecular Formula: C23H19NO4, Molecular Weight: 373.4. US Biological Life Sciences. |  Worldwide |
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