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| Product | Description | |
|---|---|---|
| Ronacaleret | Ronacaleret is a calcium-sensing receptor (CaSR) antagonist under the development of GlaxoSmithKline. It is potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34). In Jul 2015, Phase-II for Stem cell mobilisation in USA was discontinued. In Mar 2016, Phase-I for Postmenopausal osteoporosis (In volunteers) in USA was discontinued. Uses: Postmenopausal osteoporosis; stem cell mobilisation. Synonyms: SB 751689; SB751689; SB-751689; (R)-3-(3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)-4,5-difluorophenyl)propanoic acid;753449-67-1 (HCl salt). Grades: 98%. CAS No. 753449-67-1. Molecular formula: C25-H31-F2-N-O4. Mole weight: 447.52. |  |
| Ronacaleret hydrochloride | Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 751689A. CAS No. 702686-96-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15104. |  |
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