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| Product | Description | |
|---|---|---|
| Rotenone | 1g Pack Size. Group: Analytical Reagents, Biochemicals. Formula: C23H22O6. CAS No. 83-79-4. Prepack ID 26479483-1g. Molecular Weight 394.42. See USA prepack pricing. |  |
| Rotenone | ≥95%. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy; pesticides & metabolites; standards for environmental regulatory methods; food contact materials; nutritional composition compounds; pesticides & metabolites; pharma & vet compounds & metabolites; api standards. Alternative Names: 5'beta-Rotenone, Deril, (-)-cis-Rotenone, Rotenone (7CI), Rotenox, Paraderil, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy- (8CI), Nicouline, Cube-Pulver, Derris (insecticide), Rotena, CFT Legumine, Derrin, Ronone, Derris, (-)-Rotenone, Noxfish, Rotocide, NSC 26258, [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-, [2R-(2alpha,6aalpha,12aalpha)]-,(2R,6aS,12aS)-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, Rotenon, Liquid Derris, Dri-kil, NSC 8505, Tubatoxin, Dactinol. CAS No. 83-79-4. Pack Sizes: 1G, 5G, 10G, 25G. Molecular Formula: C23H22O6. Mole Weight: 394.42. EC Number: 201-501-9. Catalog: APS83794. Assay: ≥95%. SMILES: COc1cc2OC[C@H]3Oc4c5C[C@@H] (Oc5ccc4C (=O)[C@H]3c2cc1OC)C (=C)C. Format: Neat. |  |
| Rotenone | Rotenone. Group: Biochemicals. Alternative Names: (-)-Rotenone; (-)-cis-Rotenone; 5' β-Rotenone; CFT Legumine; Cube-Pulver; Dactinol; Deril; Derrin; Derris; Derris (insecticide); Dri-kil; Liquid Derris; NSC 26258; NSC 8505; Nicouline; Noxfish; Paraderil; Ronone; Rotena; Rotenon; Rotenox; Rotocide; Tubatoxin; 1,2,12,12aα-Tetrahydro-2α-isopropenyl-8,9-dimethoxy-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aαH)-one; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: Highly Purified. CAS No. 83-79-4. Pack Sizes: 2.5g. Molecular Formula: C23H22O6, Molecular Weight: 394.42. US Biological Life Sciences. |  Worldwide |
| Rotenone | Rotenone is a botanical insecticide that occurs naturally in seeds and stems of several plants. Rotenone is a mitochondrial electron transport inhibitor, inhibiting NADH/DB oxidoreductase and NADH oxidase with IC50 values of 28.8 and 5.1 nM, respectively. Synonyms: Rotenone; NSC 26258; NSC-26258; NSC26258; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: ≥95% by HPLC. CAS No. 83-79-4. Molecular formula: C23H22O6. Mole weight: 394.42. |  |
| Rotenone | Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Group: Natural products. CAS No. 83-79-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B1756. |  |
| Rotenone (Standard) | Rotenone (Standard) is the analytical standard of Rotenone. This product is intended for research and analytical applications. Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Group: Natural products. CAS No. 83-79-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1756R. | |
| Ferrostatin-1 (Ferrostatin1, Ethyl-3-amino-4- (cyclohexylamino) benzoate) | A cell-permeable 3,4-diaminoethylbenzoate-based antioxidant that effectively prevents Glutamate- (5mM; 3h) induced neurotoxicity in cultured rat OHSC (by 56%, 65%, and 71%, respectively, in CA1, CA3, and Dentrate gyrus; [Fer-1] = 2uM, added 0.5h prior to Glutamate) and Erastin- (50uM; 24h) induced HT-1080 death (EC50 = 60nM) by blocking cytosolic and lipid ROS accumulation (by >80% at 0.5uM in 10uM Erastin-treated HT-1080 cells). Fer-1 does not prevent H2O2- induced necrosis, STS-induced apoptosis, or Iron-independent oxidative death by Rotenone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Isolongifolene | Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of PI3K/AKT/GSK-3β signaling pathways. Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Isolongifolene. CAS No. 1135-66-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7363. | |
| Isolongifolene | Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of PI3K/AKT/GSK-3β signaling pathways. Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective properties. Group: Inhibitors. Alternative Names: (2S,4aR)-1,2,3,4,4a,5,6,7-Octahydro-1,1,5,5-tetramethyl-2,4a-methanonaphthalene. CAS No. 1135-66-6. Molecular formula: C15H24. Mole weight: 204.35. Appearance: Colorless or light yellow liquid. Purity: 0.95. IUPACName: (1R,8S)-2,2,7,7-Tetramethyltricyclo[6.2.1.01,6]undec-5-ene. Canonical SMILES: CC1 (C)[C@]23CC[C@] (C3) ([H])C (C) (C)C2=CCC1. Density: 0.930 g/mL at 20 °C(lit.). ECNumber: 214-494-2. Catalog: ACM1135666. |  |
| mitoNEET Inhibitor NL-1, Thiazolidinedione (5-(3,5-di-tert-butyl-4-hydroxybenzyl)-4-hydroxythiazol-2(5H)-one) | A cell-permeable, thiazolidinedione (TZD) that acts as an inhibitor of MitoNEET (IC50=0.9uM) in competition with rosiglitazone and pioglitazone, in liver mitochondrial suspensions. In pharmacological studies, it was found to alter isolated mitochondrial complex I respiration with an IC50 of 2.4uM and inhibited State III respiration up to 45%. Furthermore, this compound (6-25uM) is shown to dose-dependently reduce lactate-dehydrogenase release in SH-SY5Y cultures, leading to a 40% decrease in rotenone-induced cell-death. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Piperonylbutoxide | Piperonyl butoxide works as an insecticide synergist. It is useful in inhibitng the insect microsomal enzyme detoxification activity and is always under the combination usage with other ingredients like pyrethroid, rotenone, pyrethrin and etc. Uses: Piperonyl butoxide works as an insecticide synergist mainly for pyrethroids and rotenone. Synonyms: 5-[2-(2-butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole. Grades: > 90 %. CAS No. 51-03-6. Molecular formula: C19H30O5. Mole weight: 338.44. | |
| Piperonyl Butoxide (5-[[2- (2-Butoxyethoxy) ethoxy]methyl]-6-propyl-1, 3-benzodioxole, . ENT-14250, Butacide) | Insecticide synergist, especially for pyrethroids and rotenone. Group: Biochemicals. Alternative Names: 5-[[2- (2-Butoxyethoxy) ethoxy]methyl]-6-propyl-1, 3-benzodioxole; ENT-14250; Butacide. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Piperonyl Butoxide-d9 | Insecticide synergist, especially for pyrethroids and rotenone. Group: Biochemicals. Alternative Names: 5-[[2- (2-Butoxyethoxy) ethoxy]methyl]-6-propyl-1, 3-benzodioxole-d9; ENT-14250-d9; Butacide-d9. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H21D9O5, Molecular Weight: 347.49. US Biological Life Sciences. | Worldwide |
| PP2A Activating Ligand, ITH12246 | A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. | Worldwide |
| ST4206 | ST4206 is a potent adenosine A2A antagonist. ST4206 showed neuroprotective effects against rotenone induced alterations instriatal slice preparations,supporting the idea that adenosineA2A receptor antagonists might also be promising neuroprotective agents against the toxicity. induced bymitochondrialcomplexinhibition. Synonyms: ST4206; ST-4206; ST 4206; 2-Butanone, 4-[6-amino-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-2-yl]-. CAS No. 1246018-36-9. Molecular formula: C12H14N8O. Mole weight: 286.29. | |
| Taltirelin | Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910. CAS No. 103300-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596. | |
| Taltirelin acetate | Taltirelin acetate (TA-0910) is an acetate form of Taltirelin (TA-0910). Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910 acetate. CAS No. 1549593-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596A. | |
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