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| Product | Description | |
|---|---|---|
| Roxindole hydrochloride | Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors , with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT 1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT 1A (IC 50 =0.9 nM). Antipsychotic and antidepressant activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 38362. CAS No. 108050-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106100A. |  |
| Roxindole hydrochloride | Roxindole hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 108050-82-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Roxindole hydrochloride | Roxindole hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist, with affinity for D3, D4 and 5-HT1 receptors (pKi values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D2, D3, D4, 5-HT1A, 5-HT1B and 5-HT1D receptors). Synonyms: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-ol hydrochloride. Grades: ≥98% by HPLC. CAS No. 108050-82-4. Molecular formula: C23H26N2O.HCl. Mole weight: 382.93. |  |
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