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| Product | Description | |
|---|---|---|
| RRx-001 | RRx-001, a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes agent resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity [1]. RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α [2]. RRx-001 is a potent inhibitor of G6PD and shows potent antimalarial activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925206-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16438. |  |
| RRX-001 | RRX-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy. Synonyms: RRX001; RRX 001; RRx-001; ABDNAZ. CAS No. 925206-65-1. Molecular formula: C5H6BrN3O5. Mole weight: 268.022. |  |
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