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| Product | Description | |
|---|---|---|
| RS 127445 | RS 127445 is a high affinity, orally bioavailable, selective serotonin antagonist of 5-HT2B receptor (pIC50= 10.4) with 1000 fold selectivity over the human recombinant 5-HT2A, 5-HT2C, 5-HT5, 5-HT6 and 5-HT7 receptors. Synonyms: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine 2-amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine MT 500 MT-500 MT500 cpd RS 127445 RS 27354 RS-127445 RS-27354 RS127445 RS27354. Grades: >98 %. CAS No. 199864-87-4. Molecular formula: C17H17ClFN3. Mole weight: 317.79. |  |
| RS 127445 hydrochloride | RS 127445 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199864-86-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| RS 127445 hydrochloride | RS-127445 is a selective, high affinity, orally bioavailable serotonin 5-HT2B receptor antagonist (pKi = 9.5), which displays 1000-fold selectivity for 5-HT2B with good bioavailability. In isolated human cells, RS 127445 exbhites an IC50 greater than 10uM. Uses: Serotonin antagonists. Synonyms: RS 127445 hydrochloride; RS127445 hydrochloride; RS-127445 hydrochloride; 4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine hydrochloride; 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine Monohydrochloride; MT 500 Hydrochloride. Grades: ≥98% by HPLC. CAS No. 199864-86-3. Molecular formula: C17H16FN3.HCl. Mole weight: 317.79. | |
| RS 127445 Hydrochloride | A selective, high affinity , orally bioavailable 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi = 9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites including the closely related 5-HT2A and 5-HT2C receptors. In isolated human cells, RS-127445 exbhited an IC50 greater than 10uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 199864-86-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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