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| Product | Description | |
|---|---|---|
| RU-SKI 43 | RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh. Synonyms: RU-SKI 43; RU SKI 43; RUSKI43. Grades: >98%. CAS No. 1043797-53-0. Molecular formula: C22H30N2O2S. Mole weight: 386.55. |  |
| RU-SKI 43 hydrochloride | RU-SKI 43 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| RU-SKI 43 hydrochloride | RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC 50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782573-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18366A. |  |
| RU-SKI 43 hydrochloride | RU-SKI 43 is a potent and selective inhibitor of Hedgehog acyltransferase (HHAT). It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. Synonyms: 2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone hydrochloride. Grades: ≥98%. CAS No. 1782573-67-4. Molecular formula: C22H30N2O2S·HCl. Mole weight: 423. | |
| RU-SKI 43 maleate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
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