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| Product | Description | |
|---|---|---|
| S100 | S100. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S100. Product Category: Heterocyclic Organic Compound. CAS No. 564742-95-6. Product ID: ACM564742956. Alfa Chemistry ISO 9001:2015 Certified. |  |
| S100 Calcium Binding Protein B, Positive Control (S100B) | S100 Calcium Binding Protein B, Positive Control (S100B). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. |  Worldwide |
| ADU-S100 ammonium salt | ML RR-S2 CDA ammonium salt is an inducer of stimulator of interferon genes (STING). It can increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP, indicating the ML enhances its action at human STING. Synonyms: MIW815 ammonium salt; ML RR-S2 CDA ammonium salt; [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'?5')-adenosine, cyclic nucleotide, diammonium salt; STING Inducer-1. Grades: 98%. CAS No. 1638750-96-5. Molecular formula: C20H30N12O10P2S2. Mole weight: 724.6. |  |
| ADU-S100 disodium salt | ADU-S100 disodium salt (MIW815 disodium salt) is an activator of stimulator of interferon genes (STING) for treating cancer. Synonyms: MIW815 disodium salt; ML RR-S2 CDA disodium salt; 2',3'-c-di-AM(PS)2 (Rp,Rp); Adenosine, [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'?5')-, cyclic nucleotide, sodium salt (1:2); ADU-S 100; MIW 815. Grades: 98%. CAS No. 1638750-95-4. Molecular formula: C20H22N10Na2O10P2S2. Mole weight: 734.51. | |
| Anti-S100A12 antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-S100A1 antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-S100A6 antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-S100B antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| IsoSol-S100 Pure SemiconductingSWNT+Dielectric ink | IsoSol-S100 Pure SemiconductingSWNT+Dielectric ink. Uses: Designed for use in research and industrial production. Product Category: Purified Single-wall Carbon Nanotubes. CAS No. 7440-44-0. Product ID: ACM7440440-143. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane. | |
| Monoclonal Anti-S100A1 antibody produced in mouse | clone 1D5, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-S100A2 antibody produced in mouse | clone SH-L1, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| 23-c-di-AM(PS)2 (Rp,Rp) | 23-c-di-AM(PS)2 (Rp,Rp) (ADU-S100), an activator of stimulator of interferon genes ( STING ), leads to potent and systemic tumor regression and immunity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADU-S100; MIW815; ML RR-S2 CDA. CAS No. 1638241-89-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12885. |  |
| Amlexanox | Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to the synthesis of functional full-length proteins in an efficient manner. Selective inhibitor of TANK-binding Kinase 1 (TBK1) and IKKepsilon. Reversibly lowers weight and improves insulin sensitivity and reduces inflammation and attenuated hepatic steatosis in obese mices without affecting food intake. Group: Biochemicals. Alternative Names: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic Acid; Amoxanox; AA-673; CHX-3673; Aphthasol; Elics; Solfa. Grades: Highly Purified. CAS No. 68302-57-8. Pack Sizes: 25mg, 100mg, 500mg. Molecular Formula: C16H14N2O4, Molecular Weight: 298.29. US Biological Life Sciences. | Worldwide |
| Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX) | A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki=32nM, 96nM, and 40nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50=1.8uM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments. Group: Biochemicals. Grades: Highly Purified. CAS No. 93718-83-3. Pack Sizes: 10mg. Molecular Formula: C??H??O?S?, Molecular Weight: 310.4. US Biological Life Sciences. | Worldwide |
| Fotemustine | Fotemustine is a DNA-alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S10036. CAS No. 92118-27-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0733. | |
| Heptamidine dimethanesulfonate | Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B ( K d =6.9 μM), selectively kills melanoma cells with S100B over those without S100B [1]. Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM) [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBi4211 dimethanesulfonate. CAS No. 161374-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16918A. | |
| Paquinimod | Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215757; ABR 25757. CAS No. 248282-01-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100442. | |
| Paquinimod | Paquinimod (ABR 25757) is a specific inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Paquinimod. Product Category: Inhibitors. Appearance: Solid. CAS No. 248282-01-1. Molecular formula: C21H22N2O3. Mole weight: 0. Purity: 0.9991. Canonical SMILES: O=C(C1=C(O)C2=C(C=CC=C2CC)N(C)C1=O)N(CC)C3=CC=CC=C3. Product ID: ACM248282011. Alfa Chemistry ISO 9001:2015 Certified. | |
| Paquinimod | Paquinimod, also known as ABR - 215757, belonging to the class of quinoline-3-carboxamide derivatives, is a S100A9 inhibitor. Paquinimod is an immunomodulatory compound that reduces pathology in experimental collagenase-induced osteoarthritis. Synonyms: N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide; ABR - 215757; ABR 215757; ABR215757; Paquinimod. Grades: 95%. CAS No. 248282-01-1. Molecular formula: C21H22N2O3. Mole weight: 350.42. | |
| RAGE Antagonist, FPS-ZM1 | A blood-brain-barrier-permeant, non-toxic, tertiary amide compound that acts as a high affinity, potent, multimodal blocker of RAGE (Receptor for Advanced Glycation End products) V domain-mediated ligand binding (Ki = 25, 148, and 230nM, respectively, against Ab40, HMGB1, and S100B, binding to sRAGE). Blocks RAGE-mediated influx of Ab40 and Ab42 into the brain. Also shown to suppress Ab-RAGE induced NF-kB activation and NF-kB-dependent transcription of b-secretase. Daily treatment of APPsw/0 murine AD model (1mg/kg/d via i.p.) is reported to greatly reduce Thioflavin S-positive amyloid plaques in cortex and hippocampus (by 70 to 80%) and restore congnitive performance to the level of non-AD mice.CAS No:945714-67-0. Group: Biochemicals. Grades: Highly Purified. CAS No. 945714-67-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| RAGE Antagonist, FPS-ZM1 | RAGE Antagonist, FPS-ZM1, is a blood-brain-barrier permeant blocker of RAGE V domain-mediated ligand binding (Ki = 25, 148, & 230 nM, respectively, against A?40, HMGB1 & S100B, binding to sRAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RAGE antagonist peptide | RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1092460-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2268. | |
| RAGE antagonist peptide | RAGE antagonist peptide was produced as an inhibitor of the RAGE signaling pathway based on the RAGE-binding domain of high mobility group box-1 (HMGB1). It blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Synonyms: Ac-Glu-Leu-Lys-Val-Leu-Met-Glu-Lys-Glu-Leu-NH2. CAS No. 1092460-91-7. Molecular formula: C57H101N13O17S. Mole weight: 1272.56. | |
| Tasquinimod | Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn 2+ binding domain of HDAC4 with K d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215050. CAS No. 254964-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10528. | |
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