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Sabarubicin Sabarubicina, a disaccharide analogue of doxorubicin, is an antineoplastic agent which can intercalate into the DNA of tumor cells and interact with topoisomerase II. Synonyms: BMS195615; MEN10755. BMS 195615; MEN 10755. BMS-195615; MEN-10755. (7S,9S)-7-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione; 4-demethoxy-7-O-(2,6-dideoxy-4-O-(2,3,6-trideoxy-3-amino-alpha-L-lyxo-hexopyranosyl)-alpha-L-lyxo-hexopyranosyl)-adriamycinone; sabarubicin. Grades: >98%. CAS No. 211100-13-9. Molecular formula: C32H37NO13. Mole weight: 643.64. BOC Sciences 10
Sabarubicin Sabarubicin is a doxorubicin disaccharide analogue with striking antitumor activity. Sabarubicin is more effective than doxorubicin as a topoisomerase II poison and stimulated DNA fragmentation at lower intracellular concentrations. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 211100-13-9. Molecular formula: C32H37NO13. Mole weight: 643.64. Canonical SMILES: OC1=C2C(C(C3=CC=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)O)N)O)=C1C[C@](O)(C4)C(CO)=O. Product ID: ACM211100139. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Sabarubicin hydrochloride Sabarubicin is a disaccharide analogue of the anthracycline antineoplastic antibiotic doxorubicin. Sabarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also induces apoptosis through a p53-independent mechanism. Sabarubicin is less cardiotoxic than doxorubicin. Synonyms: BMS-195615; BMS 195615; BMS195615; MEN-10755; MEN 10755; MEN10755. CAS No. 169317-77-5. Molecular formula: C32H38ClNO13. Mole weight: 680.10. BOC Sciences 11

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