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| Product | Description | |
|---|---|---|
| Safinamide mesylate | Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 nM) [1]. Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 26743 mesylate; EMD 1195686 mesylate. CAS No. 202825-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057A. |  |
| Safinamide mesylate | Safinamide is a highly selective MAO-B inhibitor in rat brain mitochondria, with an IC50 of 98 nM. safinamide inhibits MAO-B in human brain with an IC50 of 9 nM. Synonyms: PNU-151774E; (S) -2- ( (4- ( (3-Fluorobenzyl) oxy) benzyl) amino) propanamide methanesulfonate. Grades: >98%. CAS No. 202825-46-5. Molecular formula: C17H19FN2O2.CH4O3S. Mole weight: 398.45. |  |
| Safinamide mesylate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
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