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| Product | Description | |
|---|---|---|
| SAG dihydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| SAG dihydrochloride | SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2702366-44-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12848C. |  |
| SAG dihydrochloride | SAG is a potent and cell-permeable Smoothened (Smo) receptor agonist that regulates hedgehog signaling. SAG inhibits hedgehog signaling at high concentrations. Synonyms: 3-Chloro-N-[trans-4- (methylamino) cyclohexyl]-N-[[3- (4-pyridinyl) phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride. Grades: ≥99% by HPLC. Molecular formula: C28H28ClN3OS.2HCl. Mole weight: 562.98. |  |
| SAG Dihydrochloride (Water Soluble) (N-Methyl-N?- (3-pyridinylbenzyl) -N?- (3-chlorobenzo [b]thiophene-2-carbonyl) -1, 4-diaminocyclohexane. 2HCl) | Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 364590-63-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
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