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| Product | Description | |
|---|---|---|
| SAR131675 | SAR131675 dose dependently inhibits the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC50 of about 20 nM. Synonyms: (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 1,8-Naphthyridine-3-carboxamide, 2-amino-1-ethyl-1,4-dihydro-7-[(3R)-3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl]-N-methyl-4-oxo-. Grades: >98%. CAS No. 1433953-83-3. Molecular formula: C18H22N4O4. Mole weight: 358.39. |  |
| SAR131675 | SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. Group: Biochemicals. Alternative Names: 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092538-80-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 358.39. US Biological Life Sciences. |  Worldwide |
| SAR131675 | SAR131675 is a potent and selective VEGFR3 inhibitor with an IC 50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433953-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15458. |  |
| SAR131675 (Racemate) | SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC50 values of 20 and 45 nmol/L, respectively. Synonyms: (Rac)-SAR131675; 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 1,8-Naphthyridine-3-carboxamide, 2-amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-, (±)-. Grades: ≥95%. CAS No. 1092539-44-0. Molecular formula: C18H22N4O4. Mole weight: 358.40. | |
| 2-? Amino-? 7-? chloro-? 1-? ethyl-? N-? methyl-? 4-? oxo-? 1, ? 4-? dihydro-? 1, ? 8-? naphthyridine-? 3-? carboxamide | 2-Amino-7-chloro-1-ethyl-1,4-dihydro-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide is an intermediate in the synthesis of SAR131675 (S139510), is a potent and selective VEGFR-3 inhibitor. Group: Biochemicals. Alternative Names: 2-Amino-7-chloro-1-ethyl-1,4-dihydro-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092523-24-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6-?Chloro-?2-?ethylaminonicotinic Acid | 6-?Chloro-?2-?ethylaminonicotinic Acid is an intermediate in the synthesis of SAR131675 (S139510), is a potent and selective VEGFR-3 inhibitor. Group: Biochemicals. Alternative Names: 2-(Ethylamino)-6-chloronicotinic Acid; 6-Chloro-2-(ethylamino)pyridine-3-carboxylic Acid. Grades: Highly Purified. CAS No. 1092523-21-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 6-?Chloro-?2-?(ethylamino)?pyridine-?3-?carbonyl Fluoride | 6-Chloro-2-(ethylamino)pyridine-3-carbonyl Fluoride is an intermediate in the synthesis of SAR131675 (S139510), is a potent and selective VEGFR-3 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092523-22-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
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