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Saroglitazar Saroglitazar is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia. It is approved for use in India by the Drug Controller General of India. Saroglitazar has demonstrated reduction of triglycerides (TG), LDL cholesterol, VLDL cholesterol, non-HDL cholesterol and an increase in HDL cholesterol a characteristic hallmark of atherogenic diabetic dyslipidemia (ADD). Saroglitazar is novel first in class drug which acts as a dual PPAR agonist at the subtypes α (alpha) and γ (gamma) of the peroxisome proliferator-activated receptor (PPAR). Agonist action at PPARα lowers high blood triglycerides, and agonist action on PPARγ improves insulin resistance and consequently lowers blood sugar. Group: Biochemicals. Alternative Names: (α S) -α -Ethoxy-4- [2- [2-methyl-5- [4- (methylthio) phenyl] -1H-pyrrol-1-yl] ethoxy] benzenepropanoic Acid; ZYH1; ZYH-1; ZYH 1; Lipaglyn. IUPAC/Chemical Name: (S) -2-ethoxy-3- (4- (2- (2-methyl-5- (4- (methylthio) phenyl) -1H-pyrrol-1-yl) ethoxy) phenyl) propanoic acid. Grades: Highly Purified. CAS No. 495399-09-2. Pack Sizes: 25mg. Molecular Formula: C??H??NO?S, Molecular Weight: 439.57. US Biological Life Sciences. USBiological 3
Worldwide
Saroglitazar Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment of diabetic dyslipidemia and hypertriglyceridemia with Type 2 diabetes mellitus not controlled by statin therapy. Synonyms: Lipaglyn; ZY-H1; (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid. Grades: ≥98%. CAS No. 495399-09-2. Molecular formula: C25H29NO4S. Mole weight: 439.57. BOC Sciences 10
Saroglitazar Saroglitazar is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 495399-09-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19937. MedChemExpress MCE
Saroglitazar magnesium Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639792-20-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19937A. MedChemExpress MCE
Saroglitazar (Magnesium) Saroglitazar magnesium is a dual PPAR agonist with potent predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. The first glitazar to be granted marketing authorization in India. CAS No. 1639792-20-3. Molecular formula: C50H56MgN2O8S2. Mole weight: 901.43. BOC Sciences 10

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