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| Product | Description | |
|---|---|---|
| Saxagliptin hydrochloride | Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118 hydrochloride. CAS No. 709031-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16448. |  |
| Saxagliptin hydrochloride | Saxagliptin is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP-4). It has been approved for the treatment of type 2 diabetes. It was shown to prevent the inactivation of the incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide, thus promoting insulin secretion. Synonyms: Saxagliptin HCl; BMS-477118; (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride. Grades: ≥98%. CAS No. 709031-78-7. Molecular formula: C18H25N3O2·HCl. Mole weight: 351.9. |  |
| 5-Hydroxy saxagliptin hydrochloride | 5-Hydroxy saxagliptin is a major active metabolite of saxagliptin. Grades: ≥95%. Molecular formula: C18H25N3O3·HCl. Mole weight: 367.87. | |
| (1S, 3S, 5S)-2-Azabicyclo[3. 1. 0]hexane-3-carbonitrile | Saxagliptin hydrochloride monohydrate, an anti-diabetic drug can be synthesized using a coupling reaction of (S)-phthalimido-(3-hydroxy-adamantan-1-yl)acetic acid with (1S, 3S, 5S)-2-azabicyclo[3. 1. 0]hexane-3-nitrile followed by removal of the phthalimide protecting group and treatment with HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 866083-42-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C6H8N2, Molecular Weight: 108.14. US Biological Life Sciences. |  Worldwide |
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