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SB 206553 hydrochloride SB 206553 hydrochloride is a high affinity, selective and orally active 5-HT 2B / 5-HT 2C receptor antagonist (rat 5-HT 2B pA2 = 8.89, human 5-HT 2C pKi = 7.92) [1]. SB 206553 possesses anxiolytic-like properties [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197334-04-5. Pack Sizes: 5 mg. Product ID: HY-103135. MedChemExpress MCE
SB 206553 hydrochloride SB 206553 hydrochloride is a potent and selective 5-HT2B/5-HT2C receptor antagonist (rat 5-HT2B pA2=8.89, human 5-HT2C pKi=7.92) with > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pKi < 6). Synonyms: SB 206553 HCl; SB 206553; SB206553; SB-206553; 3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride; 1-methyl-N-pyridin-3-yl-6,7-dihydropyrrolo[2,3-f]indole-5-carboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1197334-04-5. Molecular formula: C17H16N4O.HCl. Mole weight: 328.8. BOC Sciences 10
SB 206553 Hydrochloride (5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553) A selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5nM) and 5-HT2AR (Ki = 2,300nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 158942-04-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O·HCl. US Biological Life Sciences. USBiological 4
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