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| Product | Description | |
|---|---|---|
| SB 242084 hydrochloride | SB 242084 hydrochloride is a selective and brain penetrant 5-HT2C receptor antagonist with over 100-fold selectivity versus a range of other 5-HT, dopamine and adrenergic receptors. Synonyms: SB 242084 hydrochloride; SB242084 hydrochloride; SB-242084 hydrochloride; 6-chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide hydrochloride. Grades: 99%. CAS No. 1260505-34-7. Molecular formula: C21H19ClN4O2.HCl. Mole weight: 431.32. |  |
| SB 242084 Hydrochloride (5-HT2C Receptor Antagonist, SB 242084 Hydrochloride, SB-242084 Hydrochloride, SB242084 Hydrochloride) | A selective, brain-penetrant 5-HT2C receptor antagonist (pKi 8.2-9.0 ), with some effects on the 5-HT2B receptor (pKi 6.8-7.0) and 5-HT2A receptor (pKi 6.1-6.8). SB 242084 has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242,084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines. In vivo (ocular) IC50 values reported at 2.08uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 181632-25-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| SB 242084 | SB 242084 is a brain-penetrant antagonist of 5-HT2C receptor which exhibits 158-fold selectivity for 5-HT2C (pKi= 9.0) over 5-HT2A receptor (pKi= 6.1-6.8) and 100-fold selectivity over 5-HT2B receptor (pKi= 6.8-7.0). Synonyms: SB 242084; SB242084; SB-242084; 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;dihydrochloride181632-25-76-Chloro-5-methyl-N-(6-((2-methylpyridin-3-yl)oxy)pyridin-3-yl)indoline-1-carboxamide dihydrochlorideSB 242084 (hydrochloride)6-chl. CAS No. 181632-25-7. Molecular formula: C21H19ClN4O2. Mole weight: 394.85. | |
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