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SB 399885 hydrochloride SB 399885 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 402713-81-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SB 399885 hydrochloride SB 399885 hydrochloride is a brain penetrating and orally active 5-HT6 antagonist, displaying > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi = 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors, respectively). Synonyms: SB 399885 hydrochloride; SB399885 hydrochloride; SB-399885 hydrochloride; N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 402713-81-9. Molecular formula: C18H21Cl2N3O4S.HCl. Mole weight: 482.81. BOC Sciences 10
SB 399885 Hydrochloride (5-HT6 Receptor Antagonist, SB 399885) A high affinity 5-HT6 Receptor antagonist (pKi = 9.0). Good solubility (to 100mM in water or DMSO), oral availability, and penetrant to blood brain barrier. Over 200-fold selective for 5-HT6 receptors vs all receptors, ion channels and enzymes tested in Hirst et al. 2006 publication. Shows nootropic, antidepressant and axiolytic effects comparable to well-described drugs such as diazepam, and therefore has been proposed as novel treatment for schizoprenia and Alzheimer’s disease. Group: Biochemicals. Alternative Names: N- (3, 5-Dichloro-2-methoxyphenyl) -4-methoxy-3- (1-piperazinyl) benzenesulfonamide Hydrochloride; SB 399885 Monohydrochloride. Grades: Highly Purified. CAS No. 402713-80-8. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. USBiological 4
Worldwide
N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SB 399885 HYDROCHLORIDE, SureCN3202031, CTK8E8913, LS-193350, 402713-80-8. Product Category: Heterocyclic Organic Compound. CAS No. 402713-80-8. Molecular formula: 482.81. Purity: >99 %. IUPACName: N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide;hydrochloride. Canonical SMILES: COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2OC)Cl)Cl)N3CCNCC3.Cl. Product ID: ACM402713808. Alfa Chemistry — ISO 9001:2015 Certified. Categories: SB-399885. Alfa Chemistry. 5

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