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SB-216763 SB216763 is a glycogen synthase kinase-3 (GSK3) inhibitor. It can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). Synonyms: SB-216763; 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 280744-09-4. Molecular formula: C19H12Cl2N2O2. Mole weight: 371.217. BOC Sciences 11
SB 216763 (SB216763, SB-216763, SCHEMBL30251) SB 216763 is a potent and selective ATP-competitive inhibitor of glycogen synthase kinase 3 (GSK-3), including the alpha and beta isozymes. It displays neuroprotectant properties and stimulates glycogen synthesis in liver cells. SB 216763 is reported to be used to maintain the undifferentiated state of mouse embryonic stem cells. Group: Biochemicals. Alternative Names: 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione. Grades: Highly Purified. CAS No. 280744-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 9
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