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| Product | Description | |
|---|---|---|
| SB202190 | SB202190, also named FHPI, under the IUPAC name 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one, is a pyridinyl imidazole that selectively inhibits the p38α and β isoforms. IC50=50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively. Uses: A highly selective, potent and cell-permeable inhibitor of p38 map kinase(ic50 = 50 and 100 nm at sapk2a/p38 and sapk2b/p38β2) respectively). Synonyms: 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-dihydroimidazol-2-ylidene]cyclohexa-2,5-dien-1-one; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole; SB 202190; SB-202190; SB202190; SB 202190; 152121-30-7; SB-202190; SB202190; FHPI; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole; CHEBI:79090; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole; SB 202190, Immobilized; InSolution™ SB 202190; IN1110; IN1113; MFCD00941964; 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol; 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole; 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol; 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol; 4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol; C20H14FN3O; SB202190 (FHPI); SB202190, 152121-30-7; Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-i.. Grades: >98%. CAS No. 152121-30-7. Molecular formula: C20H14FN3O. Mole weight: 331.34. |  |
| SB202190 (FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole) | Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Group: Biochemicals. Alternative Names: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Grades: Highly Purified. CAS No. 152121-30-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H14FN3O. US Biological Life Sciences. |  Worldwide |
| SB 202190 | SB 202190 is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits [1] [2]. SB202190 induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152121-30-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-10295. |  |
| SB 202190 hydrochloride | SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 hydrochloride has anti-cancer activity [1] [2]. SB202190 hydrochloride induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350228-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10295A. | |
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