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SCH 529074 SCH 529074. Group: Biochemicals. Grades: Purified. CAS No. 922150-11-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SCH 529074 SCH 529074 is a small molecule activator of mutant p53 that binds p53 DNA binding domain (Kd = 1-2 μM) and restores wild-type function to many oncogenic mutants by acting as a chaperone. SCH 529074 blocks ubiquitination of p53 by HDM2, and induces apoptosis in tumor cell lines. Synonyms: SCH 529074; SCH529074; SCH-529074; N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine. Grades: ≥98% by HPLC. CAS No. 922150-11-6. Molecular formula: C31H36Cl2N6. Mole weight: 563.56. BOC Sciences 11

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