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A unique collection of 1832 annotated bioactive compounds with clear targets, suitable for phenotypic screening?- Cover more than 600 drug targets, Structurally diverse?- 2-4 structurally diversified compounds for the same annotated 'on-target' to increase the success rate of target identification (enables the generation of much stronger target-phenotype hypotheses); - Detailed information about compound structure, target, activity, etc. ?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9500. Categories: Target-Focused Phenotypic Screening Libraries.
Aldolase
enantioselectively catalyze y carbon-carbon bond formations. Group: Enzymes. Synonyms: Aldolase; DERA. Form: 1. Enzyme Powder: 8 items*50mg / item, or other quantity2. Screening Kit: 8 items*1mg / item. Aldolase; DERA; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-009.
Amidases
synthesis of chiral carboxylic acids and amides. Group: Enzymes. Synonyms: Amidases; AMD. Form: 1. Enzyme Powder: 18 items*50mg / item, or other quantity2. Screening Kit: 18 items*1mg / item. Amidases; AMD; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-003.
Approved Drug Library
A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1000. Categories: Approved Drug Libraries.
Cysteine Covalent Library
The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. In recent years, covalent chemical probes have become an important tool for drug discovery. A large number of successful applications in the evaluation of protein druggability, especially the successful application of Cys residues, bring hope for the discovery and synthesis of new covalently modified compounds. To this end, we designed a cysteine-specific covalent library. The electrophilic "warhead" of the fragments is acrylamide or chloroacetamide (25% and 75% of the library, respectively). These functional groups were chosen to construct the library because they are in the "best position" for reactivity and show selectivity in chemical proteomics screening. Uses: Scientific use. Product Category: L9411. Categories: Cysteine Covalent Libraries.
Cytochrome P450 Monooxygenase
hydroxylation (C-H activation) and oxidation of heteroatoms. Group: Enzymes. Synonyms: Cytochrome P450 Monooxygenase; CYP. Form: 1. Enzyme Powder: 8 items*50mg / item, or other quantity2. Screening Kit: 8 items*1mg / item. Cytochrome P450 Monooxygenase; CYP; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-010.
D-amino Acid Dehydrogenase
synthesis of D-amino acids from ketoacids. Group: Enzymes. Synonyms: D-amino Acid Dehydrogenase; D-AADH. Form: 1. Enzyme Powder: 17 items*50mg / item, or other quantity2. Screening Kit: 17 items*1mg / item. D-amino Acid Dehydrogenase; D-AADH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-012.
Drug Repurposing Compound Library
A unique collection of 4240 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS); - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary; - Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc. - Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc. - Detailed compound information with structure, target, activity, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9200. Categories: Drug Repurposing Compounds Libraries.
Ene Reductases
asymmetric double bond reduction. Group: Enzymes. Synonyms: Ene Reductases; ERED. Form: 1. Enzyme Powder: 29 items*50mg / item, or other quantity2. Screening Kit: 29 items*1mg / item. Ene Reductases; ERED; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-006.
Epoxide Hydrolases
synthesis of chiral alcohols from epoxides. Group: Enzymes. Synonyms: Epoxide Hydrolases; EH. Form: Enzyme Powder: 2 items*50mg / item, or other quantity. Epoxide Hydrolases; EH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-013.
FDA-Approved & Pharmacopeia Drug Library
3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc. ; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1010. Categories: FDA-Approved & Pharmacopeia Drug Libraries.
recycling NADPH and NADH. Group: Enzymes. Synonyms: Glucose Dehydrogenases; GDH. Form: Enzyme Powder: 9 items*50mg / item, or other quantity. Glucose Dehydrogenases; GDH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-015.
High Solubility 3D Diversity Fragment Library
Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this context, Fragment-based drug design (FBDD) came into being. Organic synthesis can transform miniature hits into effective lead compounds. The deficiencies in the current screening of compound libraries usually result in the need for a large amount of synthetic investment to achieve multi-directional fragment growth, which limits the efficiency of the mini-fragment hit modification process. To meet this challenge, we designed a library of highly soluble 3D structural diversity fragments. The utility of X-ray-based fragment screening and the ability to achieve rapid analog synthesis: Uses: Scientific use. Product Category: L7850. Categories: High Solubility 3D Diversity Fragment Libraries.
High Solubility Polyfunctional Group Fragment Library
Traditional drug research and development are mainly based on natural active products or screening new drugs from existing compound data, but this method is highly random, blind, and inefficient. Medicinal chemists subsequently developed high-throughput screening (HTS) methods for drug discovery. Many pharmaceutical companies have also established compound libraries containing millions of small molecules and discovered many drug candidates. However, in drug screening with complex targets, HTS has been repeatedly frustrated. It is difficult to screen high-potential compounds, or the screened compounds have high false positives and poor drug-like properties. In this ... are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. The high solubility multifunctional fragment library is designed by analyzing the spatial stability of all commercially available fragments and selecting a chemically diverse subset. In order to enhance the diversity of the compound library, we carefully selected some additional saturated heterocyclic compounds to supplement the compound library. Uses: Scientific use. Product Category: L7810. Categories: High Solubility Polyfunctional Group Fragment Libraries.
Imine Reductase
synthesis chiral amine from imine reduction form. Group: Enzymes. Synonyms: Imine Reductase; IRED. Form: Enzyme Powder: 6 items*50mg / item, or other quantity. Imine Reductase; IRED; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-022.
synthesis keto acid from lactic acid. Group: Enzymes. Synonyms: Lactate Dehydrogenase; LDH. Form: Enzyme Powder: 1 items*50mg / item, or other quantity. Lactate Dehydrogenase; LDH; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-019.
Mini Electrophilic Heterocyclic Fragment Library
The theoretical basis of FBDD is to select favorable fragment combinations or extensions to obtain new drug molecules, with a higher probability of obtaining highly active drug candidates. Compared with the screening of millions of macromolecules, thousands of fragment molecules can be combined to form millions of drug structures, which are easier to collect and manage. In addition, fragments have smaller molecular weights, relatively higher solubility, and easier structural optimization. The potential of over-the-counter medicine is higher. Targeted covalent inhibitors and chemical probes have become part of drug discovery methods. Given the advantages of fragment-based drug discovery, screening electrophilic fragments has become a promising alternative to discover and verify new targets and generate viable chemical starting points, even for targets that are almost difficult to handle. In response to this situation, we designed a small library of heterocyclic electrophilic compounds. General technology for covalent fragment screening ?. Uses: Scientific use. Product Category: L7860. Categories: Mini Electrophilic Heterocyclic Fragment Libraries.
Nitrilases
synthesis of chiral carboxylic acids from nitriles. Group: Enzymes. Synonyms: Nitrilases; NIT. Form: 1. Enzyme Powder: 40 items*50mg / item, or other quantity2. Screening Kit: 40 items*1mg / item. Nitrilases; NIT; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-005.
Nitrile Hydratases
synthesis of chiral amides from nitriles. Group: Enzymes. Synonyms: Nitrile Hydratases; NHT. Form: 1. Enzyme Powder: 24 items*50mg / item, or other quantity2. Screening Kit: 24 items*1mg / item. Nitrile Hydratases; NHT; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-004.
Nitro Reductases
synthesis of amines from nitro compounds. Group: Enzymes. Synonyms: Nitro Reductases; NTR. Form: 1. Enzyme Powder: 12 items*50mg / item, or other quantity2. Screening Kit: 12 items*1mg / item. Nitro Reductases; NTR; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-008.
ω-Transaminases
synthesis of chiral amines from ketones and ketoacids. Group: Zymogens. Synonyms: ω-Transaminases; ATA. Form: 1. Enzyme Powder: 58 items*50mg / item, or other quantity2. Screening Kit I: 58 items*1mg / item3. Screening Kit II: 39 items*1mg / item. ω-Transaminases; ATA; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-002.
Oxynitrilases
synthesis of chiral cyanohydrins from aldehydes. Group: Enzymes. Synonyms: Oxynitrilases; HNL. Form: 1. Enzyme Powder: 29 items*50mg / item, or other quantity2. Screening Kit I: 18 (S) alcohol nitrile item * 1 mg/item3. Screening Kit II: 11 (R) alcohol nitrile item * 1 mg/item. Oxynitrilases; HNL; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-007.
Pig Liver Esterase
ester compounds will be hydrolyzed to chiral acid. Group: Enzymes. Synonyms: Pig Liver Esterase; PLE. Form: 1. Enzyme Powder: 14 items*50mg / item, or other quantity2. Screening Kit: 14 items*1mg / item. Pig Liver Esterase; PLE; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-014.
Selectable Natural Product Library
A unique collection of 19377 pure natural products with diverse structures and sources covering various plant, animal, and microbe species; - Free SDF data available for each compound structure in this library, an effective tool for virtual screening; - All products can be resupplied; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6020. Categories: Selectable Natural Product Libraries.
Threonine Dehydrogenase
synthesis keto acid from threonine. Group: Enzymes. Synonyms: Threonine Dehydrogenase; TDA. Form: Enzyme Powder: 1 items*50mg / item, or other quantity. Threonine Dehydrogenase; TDA; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-021.
1-Amino-1-cyclopropanecarboxylic acid
1-Aminocyclopropane-1-carboxylic Acid is a plant growth regulator and an NMDA agonist acting at the glycine site (1). It is also a useful compound to develop DNA-encoded small molecule libraries for screening enzyme inhibitors (2). Group: Biochemicals. Alternative Names: 1-Aminocyclopropane carboxylic Acid; 1-Amino-1-carboxycyclopropane; 1-Aminocyclopropane-1-carboxylate; 1-Aminocyclopropane carboxylic Acid; ACC; ACPC; NSC 98430; α -Aminocyclopropane carboxylic Acid. Grades: Highly Purified. CAS No. 22059-21-8. Pack Sizes: 5g, 10g, 25g, 50g. Molecular Formula: C?H?NO?, Molecular Weight: 101.1. US Biological Life Sciences.
Worldwide
Adrenergic Receptor-Targeted Compound Library
A unique collection of 219 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2700. Categories: Adrenergic Receptor-Targeted Compounds Libraries.
Alkaloid Natural Product Library
A unique collection of 317 natural alkaloids can be used for high throughput and high content screening?- Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6110. Categories: Alkaloid Natural Product Libraries.
Angiogenesis related Compound Library
A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries.
Anti-Aging Compound Library
A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS); - Targets cover various aging-related processes, such as cell protective, DNA damage repair, and stem cell induction, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8200. Categories: Anti-Aging Compounds Libraries.
Antibiotics Library
A unique collection of 708 compounds with antibiotic activity for new antibacterial drug screening; - Most of them are approved to be marketed, and some of which are FDA approved. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4400. Categories: Antibiotics Libraries.
Anti-Cancer Active Compound Library
A unique collection of 2114 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2160. Categories: Anti-Cancer Active Compounds Libraries.
Anti-Cancer Approved Drug Library
A unique collection of 1726 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); - These FDA, EMA, or NMPA approved anti-cancer drugs have annotated bioactivity, safety, and bioavailability; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2110. Categories: Anti-Cancer Approved Drug Libraries.
Anti-Cancer Clinical Compound Library
A unique collection of 1990 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers; - Effective tool for cancer research and drug repurposing screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. , in lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2120. Categories: Anti-Cancer Clinical Compounds Libraries.
Anti-Cancer Compound Library
A unique collection of 5885 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials); - Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2100. Categories: Anti-Cancer Compounds Libraries.
Anti-Cancer Drug Library
A unique collection of 2478 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials), an effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug repositioning drug discovery; - Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc; involved in 15 different cancer research areas, such as lung cancer, breast cancer, leukemia, lymphoma, etc. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2150. Categories: Anti-Cancer Drug Libraries.
Anti-Cancer Metabolism Compound Library
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Covers 16 major targets related to cancer cellular metabolism (glucose, proteins, lipids and nucleic acids) including ACL, CA, FASN, GLUT, GLS, HMG-CoA, MAGL, MCTs, PDH, PDK, PKM, etc. ; Effect tool for research in cancer metabolism and anti-cancer drug screening. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2130. Categories: Anti-Cancer Metabolism Compounds Libraries.
Anti-Cardiovascular Disease Compound Library
A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA; - Covers various major targets including membrane transporter, ion channel, etc. ; Effect tool for research in cardiovascular disease. - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5400. Categories: Anti-Cardiovascular Disease Compounds Libraries.
Anti-COVID-19 Traditional Chinese Medicine Compound Library
A unique collection of 1162 monomers from 70 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening?- Sources are 70 TCM plants including Lonicera japonica Thunb. , Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc. ?- Structurally diverse: including Flavonoids, alkaloids, Polyphenols, Terpenes, ets. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6720. Categories: Anti-COVID-19 Traditional Chinese Medicine Compounds Libraries.
Anti-Fungal Compound Library
A unique collection of 253 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation. - Contains antifungal agents to treat tinea corporis and Candidiasis, and compounds inhibiting the fungal-specific targets. - Bioactivity and safety confirmed by clinical research and trials, some of which are FDA approved; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4500. Categories: Anti-Fungal Compounds Libraries.
Anti-Gastroenteritis Natural Product Library
A unique collection of 223 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); - Effective tool for research in gastric function and gastric diseases, such as gastritis, gastric ulceration, Crohns disease, ulcerative colitis, appendicitis, etc. - Bioactivity and safety profiled in pre-clinical and clinical settings; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6600. Categories: Anti-Gastroenteritis Natural Product Libraries.
Anti-Hypertension Compound Library
719 hypertension-related small molecules for high-throughput and high-content screening. - Targets include ACE, calcium channel, β-adrenergic receptor, HMG-CoA Reductase, etc. - Detailed instructions, compound structure, target information, activity description, etc. - NMR and HPLC analytical techniques to ensure high product purity and quality. - All compounds are available in stock. Uses: Scientific use. Product Category: L7110. Categories: Anti-Hypertension Compounds Libraries.
Anti-Infection Compound Library
A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; - Effective tool for new anti-infective drugs high throughput screening and high content screening, containing sulfonamides, tetracyclines, aminoglycosides, and macrolide derivatives, etc. - Bioactivity and safety confirmed by clinical research and trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1800. Categories: Anti-Infection Compounds Libraries.
Anti-Metabolism Disease Compound Library
A unique collection of 1558 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA; - Covers various major targets including CYP, FAAH, IDO, MAO, etc. , in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc. ; Effective tool for cell metabolism research; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5200. Categories: Anti-Metabolism Disease Compounds Libraries.
Anti-Obesity Compound Library
A unique collection of 1359 anti-obesity compounds for high throughput and high content screening; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7100. Categories: Anti-Obesity Compounds Libraries.
Antioxidant Compound Library
A unique collection of 1040 antioxidant bioactive small molecule compounds for high-throughput, high-content screening. - Targets include mTOR, Keap1-Nrf2, ROS, NF-κB, etc. - Structural diversity, significant drug potency with cell permeability. - Detailed instruction manual, compound structure, target information, activity description, etc. - Multiple detection techniques such as NMR and HPLC/LCMS to ensure the accurate structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L2910. Categories: Antioxidant Compounds Libraries.
Anti-Tumor Natural Product Library
A unique collection of 1471 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Cost-effectiveness: expensive natural products with poor drug likeliness are excluded, allowing for more high-quality natural products at a lower cost. Uses: Scientific use. Product Category: L6700. Categories: Anti-Tumor Natural Product Libraries.
Anti-Virus Compound Library
Quantity: A unique collection of 800 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening; - Target viruses include HBV, HCV, HIV, HSV, Influenza Virus, Reverse Transcriptase, etc. covering more than 140 targets; - Structurally diverse and strong bioactivity; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description, providing reference for your experimental design; - NMR and HPLC/LCMS validated to ensure high purity and quality. - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1700. Categories: Anti-Virus Compounds Libraries.
Apoptosis Compound Library
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; - Targets include Bcl-2, Caspase, p53, TNF-alpha, and surviving, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9000. Categories: Apoptosis Compounds Libraries.
Autophagy Compound Library
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3200. Categories: Autophagy Compounds Libraries.
Bioactive Compound Library
A collection of 11585 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification; - All compounds have clear targets; - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc. - Detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4000. Categories: Bioactive Compounds Libraries.
Bioactive Compounds Library Max
A collection of 19703 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. - All compounds are described with corresponding target information, which makes activity studies more evidence-based. - An effective tool for drug repurposing and cell-induced target screening. - Covers multiple areas of disease studies, such as cancer, metabolism, immune system and cardiovascular system. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant drug potency and cell penetration. Uses: Scientific use. Product Category: L4010. Categories: Bioactive Compounds Libraries Max.
Bioactive Lipid Compound Library
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, HETEs deHETEs, hepoxilins, Polyunsaturated fatty acids, Leukotrienes, lipoxins, LPA & phosphatidic acids, Octadecanoids, PAFs, Prostaglandins & thromboxanes, Retinoids, vitamin D metabolites, Sphingolipids, etc. ; - Targets include GPCR, HDAC, PPAR, DNA Alkylating, EGFR, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7000. Categories: Bioactive Lipid Compounds Libraries.
Calcium Antagonist Library
A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening; - Targeting different subtypes of calcium channels, such as L-type, T-type, N-type, and receptor-operated calcium channels. - Bioactivity and safety confirmed by pre-clinical research and clinical trials, some of which are FDA approved; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7200. Categories: Calcium Antagonist Libraries.
Cancer Cell Differentiation Compound Library
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2140. Categories: Cancer Cell Differentiation Compounds Libraries.
Cell Cycle Compound Library
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc. ; - Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8100. Categories: Cell Cycle Compounds Libraries.
Chemokine Inhibitor Library
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; - Targets include chemokines and their receptors, such as CCR, CXCR, CR, CX3CR, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7600. Categories: Chemokine Inhibitor Libraries.
Chemotherapy Drug Library
51 Chemotherapeutic drugs that can be used for high-throughput and high-content screening. - Includes common chemotherapy drugs such as paclitaxel, cyclophosphamide, cytarabine, doxorubicin, etc. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure correct structure, high purity and reduce the false-positive rates. Uses: Scientific use. Product Category: L2151. Categories: Chemotherapy Drug Libraries.
Chromatin Modification Compound Library
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8300. Categories: Chromatin Modification Compounds Libraries.
Clinical Compound Library
A unique collection of 3142 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS); - All compounds have been permitted into clinical trial phases, categorized into Phase 1, Phase 2 and Phase 3. - An effective tool for new drug screening and cell differentiation induction; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3400. Categories: Clinical Compounds Libraries.
CNS-Penetrant Compound Library
A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include Kinases, GPCR, and ion channels, etc. ; - Effective tool for drug screening in brain disorders, such as brain tumor, mental disorders, and neurodegenerative diseases, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable and CNS penetrant; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5900. Categories: CNS-Penetrant Compounds Libraries.
Coagulation and Anticoagulation Compound Library
A unique collection of 154 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS); - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7500. Categories: Coagulation and Anticoagulation Compounds Libraries.
Covalent Natural Product Library
Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research. - Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information. - Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost. - Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc. Uses: Scientific use. Product Category: L6150. Categories: Covalent Natural Product Libraries.
Cuproptosis Compound Library
411 active small molecules associated with cuproptosis for high-throughput and high-intensity screening. - Targeting Ferredoxin 1 (FDX1), Antioxidant 1 Copper Chaperone (ATOX1), CCS (copper chaperones), mitochondrial respiration, etc. - Some compounds are FDA-approved. - Detailed instructions, compound structure, target information, description of activity, etc. - Various detection techniques such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L8710. Categories: Cuproptosis Compounds Libraries.
Cytokine Inhibitor Library
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and most of them are approved to be marketed; - Targets cover various cytokines including IL, CSF, IFN, TNF, TGF-beta family, growth factors, chemokine family, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3600. Categories: Cytokine Inhibitor Libraries.
DNA Damage & Repair Compound Library
A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3900. Categories: DNA Damage & Repair Compounds Libraries.
Drug-Fragment Library
Quantity: 1159 drug fragments?a must-have tool for FBDD; - Physiochemical properties: 53% of fragments are Ro3 compliant?and all fragments matching with approved drugs or clinical compounds will have the best drug potential; - Quality guaranteed: NMR and HPLC/LCMS validated to ensure high purity and quality; - Applicable to various detection methods: suitable for SPR, NMR, and X-ray crystallization screening. Uses: Scientific use. Product Category: L8800. Categories: Drug-Fragment Libraries.
Drug-induced Liver Injury (DILI) Compound Library
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening?- Include anti-cancer drugs, antibiotics, antituberculotic agents, antiretrovirals, antiepileptic agents, and cardiac medications, etc. ?- Diversified in toxicities: Steatosis, Mitochondrial toxicity, cholestasis, drug allergy (hypersensitivity), etc. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5510. Categories: Drug-induced Liver Injury (DILI) Compounds Libraries.
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