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| Product | Description | |
|---|---|---|
| SDZ NKT 343 | SDZ NKT 343. Group: Biochemicals. Grades: Purified. CAS No. 180046-99-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| SDZ NKT 343 | SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist (IC50 = 0.62 and 451 nM for human and rat receptors, respectively), displaying > 130-fold selectivity over human NK2 and NK3 receptors. SDZ NKT 343 was shown to antagonize SP-induced Ca2+ efflux in vitro and inhibit mechanical hyperalgesia in vivo. Uses: Neurokinin-1 receptor antagonists. Synonyms: 1-[[(2-Nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide. Grades: ≥98% by HPLC. CAS No. 180046-99-5. Molecular formula: C33H33N5O5. Mole weight: 579.65. |  |
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