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| Product | Description | |
|---|---|---|
| Seladelpar | Seladelpar is a selective peroxisome proliferator-activated receptor -δ receptor agonist. Phase II clinical trials for the treatment of Hyperlipidaemia, Hyperlipoproteinaemia type IIa and Primary biliary cirrhosis were on-going. Synonyms: MBX8025; RWJ800025; MBX 8025; RWJ 800025; MBX-8025; RWJ-800025; (R) -2- (4- ( (2-ethoxy-3- (4- (trifluoromethyl) phenoxy) propyl) thio) -2-methylphenoxy) acetic acid. Grades: 98%. CAS No. 851528-79-5. Molecular formula: C21H23F3O5S. Mole weight: 444.46. |  |
| Seladelpar | Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025; RWJ-800025. CAS No. 851528-79-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19522. |  |
| Seladelpar (lysine) | Seladelpar (MBX-8025) lysine is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM. Seladelpar lysine shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 (lysine). CAS No. 928821-41-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19522B. | |
| Seladelpar Lysine dihydrate | Seladelpar (MBX-8025) Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ , with EC 50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate. CAS No. 928821-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19522C. | |
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