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SEN 12333 SEN 12333. Group: Biochemicals. Grades: Purified. CAS No. 874450-44-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SEN 12333 SEN 12333 is a brain penetrating and orally bioactive α7 nicotinic acetylcholine receptor (nAChR) agonist (EC50 = 1.6 μM, Ki = 260 nM at rat α7 nAChRs) exhibiting neuroprotective property. SEN 12333 also displays functional antagonist activity at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Synonyms: WAY 317538; SEN 12333; WAY317538; SEN12333; WAY-317538; SEN-12333; N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide; 5-morpholin-4-yl-N-(4-pyridin-3-ylphenyl)pentanamide. Grades: ≥99% by HPLC. CAS No. 874450-44-9. Molecular formula: C20H25N3O2. Mole weight: 339.43. BOC Sciences 10

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